About this opportunity
Vivatides Therapeutics Inc. lists this Associate Director/Director/Senior Director/Executive Director, Oligonucleotide Chemistry opportunity in woburn, Massachusetts. Review the employer’s description below for duties, qualifications and application requirements.
Job description
As an exciting start-up, we offer amazing opportunity to develop the next generation RNA therapeutics. We are seeking a well-organized and self-motivated chemist to join our company site in Woburn, MA. The successful candidate will be a key member of the drug discovery group and will lead efforts to advance siRNA/ASO therapeutics to treat intractable diseases. Strong knowledge of oligonucleotide drug design and experience in organic chemistry of oligonucleotide precursors, respective delivery vehicles and methods is a must. Experience in oligonucleotide post-conjugation methods is a strong plus. Experience of work with oligo synthesizers is a plus but not required. Proven track record of leadership of successful projects in oligonucleotide drug discovery and strong publication record of scientific papers and patents.
Primary Responsibilities
Chemistry platform design and refining, covering delivery ligand, linker and chemical modification.
Oversee team performance.
Manage FFS/FTE projects with CROs.
Chemistry informatics (Literature and patent search).
Drafting patent applications.
Refine company standards of data collection, presentation, and QC.
May need to establish new specialized chemistry units, screen/recruit candidate chemists.
CMC collaboration and planning.
Qualifications
Ph.D. in Organic or Medicinal Chemistry.
Minimum of 5 years of experience in oligonucleotide drug discovery, with at least 2 years in a leadership role.
Comprehensive experience in delivery ligand and linker development
Deep understanding of oligonucleotide and precursor synthesis, modification, purification, and conjugation mechanisms.
Familiarity with analytical methods and quality standards in oligonucleotide drug development.
Strong project management skills and cross-functional communication abilities; International collaboration experience is preferred.
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Worksite address
woburn, MA, 01813, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.