About this opportunity
Scorpion Therapeutics lists this Associate Director, Quantitative Systems Pharmacology opportunity in cambridge, Massachusetts. Review the employer’s description below for duties, qualifications and application requirements.
Job description
Overview:
The Associate Director, Quantitative Systems Pharmacology (QSP) supports a clinical portfolio of RNAi therapeutics. The role applies systems pharmacology, clinical pharmacology, PK/PD, and data analysis to answer drug development questions across all stages.
Key Responsibilities:
Strategize, formulate, and execute QSP modeling and simulation for dose selection, trial design, mechanistic understanding (disease–biomarker–response), and prediction of clinical outcomes.
Partner with clinical pharmacologists, pharmacometricians, and research/clinical/nonclinical modelers to identify and interpret preclinical and clinical data and guide data generation for QSP model building/refinement.
Build and utilize QSP models to understand disease pathways and treatment effects; independently analyze, interpret, and report results for internal decisions.
Stay current on QSP methodologies; serve as a technical leader and mentor team members.
Increase internal/external visibility through peer-reviewed publications and scientific presentations.
Explore synergy between QSP and other modeling approaches to inform development decisions.
Qualifications:
Ph.D. (or equivalent) in applied mathematics, biomedical engineering, systems biology/pharmacology, or related field.
5+ years in pharmaceutical industry, consulting, or regulatory agency.
Track record using QSP modeling to impact drug development decisions.
Required/Preferred Skills:
Strong systems biology/physiology/PK/PD knowledge; foundation in theory, statistics, differential equation-based modeling, and parameter estimation/optimization.
Extensive hands-on QSP modeling experience (e.g., R, MATLAB, Simbiology).
Ability to translate QSP outcomes for project teams; strong collaboration, interpersonal, and written/oral communication skills.
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Worksite address
cambridge, MA, 02140, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.