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Job description
The Regeneron Genetic Center's (RGC) Genome Informatics team is looking for an Associate Manager of Sequencing Informatics Research to serve as the lead scientist and developer for the RGC’s Sequencing Informatics research initiatives. This individual will contribute to development and design of sequencing informatics methods and protocols for new and existing multi-omics platforms, including PacBio, Illumina, Olink, and Ultima. These efforts will be driven by the goal to maximize value from RGC samples and data.
Working closely with the Sequencing & Lab Operations and Production Informatics teams, this role will also assist the methods engagement with RGC’s technology partners to on-board new sequencing and informatics platforms and ensure they can meet the RGC’s unique scaling and analysis needs.
When & Where
Location: Tarrytown, NY
Work model/flexibility: 4 days onsite
Discover Your Role
Lead the integration of state-of-the‑art and novel methods to create multi‑omics informatics best‑practices that increase value from RGC samples by lowering data requirements and leveraging RGC’s unique data resources
Identify opportunities that combine multiple sequencing modalities (e.g., short‑read, long‑read, capture, genome, depth‑based) to increase the actionability of RGC sequencing deliverables
Inform development of novel sequencing informatics protocols to support multi‑omics applications on existing and new sequencing platforms, including DNA‑seq, RNA‑seq, long‑read sequencing, and proteomics
Support RGC’s joint development efforts with technology partners (e.g. NVIDIA, Google Brain) to improve base‑calling, read mapping, variant calling and harmonization through bioinformatics R&D
Collaborate with RGC’s Genomics R&D, Engineering and Production teams to deploy novel methods into the RGC’s Enterprise Research environment as industry‑quality software
This Role Requires
Master’s (PhD preferred) in Bioinformatics or equivalent
0‑3 years of experience in sequencing informatics methodology, including base calling, read mapping, and variant calling algorithms and software.
Experience with large‑scale multi‑omics data types, including DNA‑seq (short and long read), RNA‑seq, proteomics, methylation.
Expert fluency in state-of-the‑art bioinformatic tools and standards.
Demonstrated engagement in the sequencing bioinformatics community.
Experience creating or adapting novel bioinformatic data structures and file formats to improve actionability.
We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.
Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.
Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.
As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.
For jobs in Canada: this posting is for an existing position.
Salary Range (annually)
$109,900.00 - $179,300.00
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Who can apply
Review the original listing for work authorization, qualifications and employer requirements.