About this opportunity
InVitro Cell Research, LLC lists this Associate Principal Scientist, Regenerative Immunology opportunity in englewood, New Jersey. Review the employer’s description below for duties, qualifications and application requirements.
Job description
ICR's Regenerative Immunology program is focused on regenerating the aging immune system, the decline of which underlies many of the most devastating age-related diseases. We're hiring a Principal Scientist to lead our Thymic Regeneration Team to restore thymic function and rejuvenate adaptive immunity. You'll need a deep background in immunology, thymic biology and iPSCs.
With ICR, you'll get to:
Lead a cutting-edge team developing iPSC-derived thymic epithelial cells (iTECs) and thymic organoids to rejuvenate the aging immune system
Contribute highly practical and readily translatable thymic regeneration, immune reconstitution and rejuvenative medicine ideas
Design and optimize directed-differentiation protocols to generate functional, TECs from human iPSCs
Build, characterize and validate 3D thymic organoids capable of supporting de novo T-cell development
Collaborate with other ICR scientists and groups to advance immune rejuvenation under a personalized medicine paradigm
Please apply if you have:
A PhD or MD/PhD
At least 10 years of research experience, preferably in thymic biology, stem cell differentiation, organoid engineering or regenerative immunology
Current and in-depth knowledge of thymic epithelial cell biology, iPSC directed differentiation, T-cell development and tissue engineering
Ideally, you'll also have:
Expert knowledge of thymic epithelial cell ontogeny, FOXN1 biology, T-cell selection and thymic niche reconstitution
Experience with iPSC culture, directed differentiation, 3D organoid culture, single-cell genomics, RNAseq, flow cytometry, immunofluorescent microscopy, CRISPR gene editing and cell culture
Experience with in vivo transplantation, humanized mouse models and assessment of functional immune reconstitution
Even if you don't meet all of these criteria, please apply anyway
And you'll need:
An easygoing, friendly personality
The ability to work in the United States without sponsorship
If you don't combine your cover letter with your CV or resume when you apply through LinkedIn, after you apply please send your cover letter only to: with "Cover (Your name)" as the Subject line.
Position title and compensation are commensurate with experience.
The compensation ranges listed below are starting ranges.
Starting base pay range: $160,000/yr - $215,000/yr
Starting bonus range: $10,000/yr - $20,000/yr
Why join ICR?
EXERCISE your intellect in challenging and rewarding science
ENTER an career dedicated to a mission that matters to everyone
ENGAGE in cutting-edge regenerative medicine research
EXCELLENT research environment, salaries and relocation expenses (fully covered!)
Worksite address
englewood, NJ, 07631, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.