About this opportunity
MSD lists this Associate Scientist, Post Doc Fellow- Translational Neuroscience opportunity in west point, Pennsylvania. Review the employer’s description below for duties, qualifications and application requirements.
Job description
Postdoctoral Fellow, Translational Neuroscience
Position Overview
We are seeking a highly motivated and innovative Postdoctoral Fellow in Neuroscience to join our Discovery Biology team. This laboratory-based position offers an exciting opportunity to advance novel therapies for neurodegenerative diseases through cutting-edge preclinical and translational research.
The successful candidate will have strong expertise in neurodegeneration, animal models, translational biomarkers, and in vivo neuroimaging. They will independently design and execute studies, generate mechanistic insights into disease biology, and collaborate across multidisciplinary teams to support CNS drug discovery programs. With access to state‑of‑the‑art biology and neuroimaging technologies, the candidate will generate critical insights into disease pathology and therapeutic efficacy, helping to shape the future of how we understand, visualize, and ultimately treat certain neurodegenerative diseases.
Key Responsibilities
Design and conduct preclinical studies using rodent models of neurodegenerative diseases.
Perform hands‑on in vivo experiments, including dosing, tissue collection, and downstream biomarker analyses.
Apply biochemical and molecular techniques, including ELISA, Meso Scale Discovery, immunohistochemistry, and ultrasensitive biomarker assays.
Develop and utilize in vivo MRI methods to evaluate neuroinflammation, blood‑brain barrier integrity, and other translational endpoints.
Integrate imaging, fluid biomarker, and pharmacological datasets to uncover disease mechanisms and therapeutic responses.
Collaborate with scientists across neuroscience, translational imaging, pharmacology, and data science to generate scientific insights that influence project strategy and decision‑making.
Present findings through internal presentations, scientific conferences, and peer‑reviewed publications.
Education Requirements
Must currently hold a Ph.D. OR
Receive a Ph.D. no later than spring 2027
Ph.D. in Neuroscience, Pharmacology, Biomedical Sciences, or a related discipline.
Required Skills & Experience
Expertise with rodent models of neurodegenerative disease.
Strong hands‑on experience with molecular and cellular biology techniques, such as ELISA, Meso Scale Discovery, immunohistochemistry, and/or Quanterix‑based assays.
Hands‑on experience with MRI or other translational imaging approaches.
Understanding of PK/PD principles and translational pharmacology.
Proficiency in data analysis and visualization tools, such as GraphPad Prism, HALO, and image analysis using MATLAB and/or Python.
Demonstrated ability to independently design, execute, and troubleshoot complex studies.
Strong scientific communication skills, evidenced by publications and presentations.
Preferred Skills & Experience
Experience with translational biomarkers and mechanism‑based drug development.
Experience with transcriptomics, proteomics, or multi‑omics data generation and analysis.
Research experience in Alzheimer's disease, Parkinson's disease, ALS, or related CNS disorders.
Experience working in multidisciplinary drug discovery teams.
Demonstrated ability to lead collaborative projects and coordinate activities across scientific functions.
Salary
The salary range for this role is: $82,000- $92,000
This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.
The successful candidate will be eligible for annual bonus and long‑term incentive, if applicable.
Benefits
We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days.
Required Skills
Biomarkers, Data Analysis, Design of Experiments (DOE), Disease Models, Immunoassays, In Vivo Models, Neurodegeneration, Neuroinflammation, Scientific Research, Statistical Analysis
US and Puerto Rico Residents Only
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.
Equal Employment Opportunity Statement
As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement
San Francisco Residents Only
We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
Los Angeles Residents Only
We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance
Employee Status
Employee Status: Regular
Relocation: Domestic
VISA Sponsorship: Yes
Travel Requirements: 10%
Flexible Work Arrangements: Not Applicable
Shift: Not Indicated
Valid Driving License: No
Hazardous Material(s): N/A
Job Posting End Date: 10/12/2026*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
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Worksite address
west point, PA, 19486, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.