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Soufflé Therapeutics

Associate Scientist, Protein Conjugation and Purification

watertown, MA

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About this opportunity

Soufflé Therapeutics lists this Associate Scientist, Protein Conjugation and Purification opportunity in watertown, Massachusetts. Review the employer’s description below for duties, qualifications and application requirements.

Job description

Soufflé Therapeutics | Associate Scientist, Protein Conjugation and Purification | Job Description

Soufflé Therapeutics is a biotech company focusing on the cell-type specific delivery of genetic medicines. It's team of driven scientists is making a mark in delivery of oligonucleotides to extrahepatic tissues. We thrive in a purpose-building lab and office space in Watertown. Come and join us in our quest!

Position Summary:

As Soufflé Therapeutics grows its research pipeline – targeting more tissues and taking on more collaborations – we need hands-on support producing, purifying, and characterizing protein bioconjugates. As our new Associate Scientist, Protein Conjugation and Purification, you'll be a key contributor to that pipeline, generating and purifying material that directly supports our in vitro and in vivo studies. If you want to build your bioconjugation and purification skills in a fast-paced, high-impact environment, this is a great place to start.

Key Responsibilities

Purify and characterize protein bioconjugates to support Soufflé's in vitro and in vivo studies

Develop and optimize methods for the preparation and purification of bioconjugates

Generate protein bioconjugates using a range of conjugation chemistries

Characterize conjugates using techniques such as SEC-HPLC, SDS-PAGE, and mass spectrometry

Present data to colleagues and coordinate efforts with other teams

What Success Looks Like

In 3 months: You're acquainted with our basic protein science workflows, protocols, and instrumentation

In 6 months: You're carrying out routine lab work independently, with minimal supervision

In 12 months: You're independently troubleshooting issues and owning experimental projects with minimal oversight, with a mature understanding of how your work fits into Soufflé's broader efforts

Qualifications — Required

Some hands-on experience with protein chemistry, including FPLC, HPLC, and TFF

Strong troubleshooting skills

Education

BS + 1 year of relevant experience, or a completed MS, in biochemistry, biotechnology, chemistry, or a related field

At Soufflé Therapeutics, we are intentional about building an equitable culture. How we treat our people is reflective of this focus. We are an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

This is an onsite position in Watertown, MA (US) with flexibility as needed for collaboration and external engagements.

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Worksite address

watertown, MA, 02472, US

Who can apply

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