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Structure Therapeutics, Inc.

Director, Clinical Trial Finance

south san francisco, CA

Check who can apply and the requirements below before continuing.

About this opportunity

Structure Therapeutics, Inc. lists this Director, Clinical Trial Finance opportunity in south san francisco, California. Review the employer’s description below for duties, qualifications and application requirements.

Job description

About Us:

StructureTherapeutics develops life‐changing medicines for patients using advanced structure‐based and computational drug discovery technology. The company’s platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs. We are advancing a clinical‐stage pipeline of differentiated treatments focused on chronic diseases with high unmet need, including cardiovascular, metabolic, and pulmonary conditions.

Structure Therapeutics is led by an experienced group of international drug innovators and financed by top‑tier global life sciences investors. The company completed an initial public offering (IPO) in February 2023. With offices in California and Shanghai, Structure Therapeutics has the benefit of being at the center of life science innovation in both the US and China and capitalizing on the strengths of each geographic location. Reporting directly or operationally into the Executive Director, FP&A, the role supports the broader coordination of efforts across teams to ensure impactful contributions to AI integration

Position Summary:

The Director, Clinical Trial Finance will lead financial planning and oversight of clinical trial activities, including accruals, in support of the company’s development portfolio. Reporting to the Executive Director, FP&A, this role serves as a key strategic partner to Clinical Operations, Development, FP&A, and Accounting, ensuring strong financial governance, accurate reporting, and actionable insights to inform decision‑making.

The ideal candidate brings deep expertise in biotech finance, a thorough understanding of clinical development, and a strategic, hands‑on approach to driving financial performance in a dynamic, growth‑oriented environment.

This is an opportunity to play a critical role in advancing a global, publicly traded biotech company’s pipeline and supporting the successful execution of clinical programs.

Job Responsibilities:

Drive financial planning, budgeting, forecasting, and long‑range planning for clinical trials; oversee financial management across programs, including accruals and variance analysis, in alignment with corporate objectives.

Oversee financial management of clinical trial contracts, amendments, and compliance with financial terms.

Partner closely with Accounting to ensure accurate and timely financial close processes, including journal entries, reconciliations, and reporting of clinical trial costs.

Serve as the primary finance business partner to Clinical Operations, Development, and Program Management, providing insights and ad hoc financial reporting to support decision‑making.

Establish and maintain strong relationships with Contract Research Organizations (CROs), vendors, and external partners.

Collaborate across Clinical organization to define key financial drivers, timelines and milestones for clinical trials.

Lead audit readiness efforts and support internal and external audits related to clinical trial expenditures.

Continuously enhance financial processes, systems, and internal controls to support scalability and operational excellence.

Qualifications:

Experience

10+ years of finance experience, including 7+ years in increasingly responsible roles within finance and accounting, with significant experience supporting clinical trials in the biotech or pharmaceutical industry.

Deep industry experience with strong understanding of clinical development, industry dynamics, and key financial drivers.

Strong knowledge of GAAP and SOX compliance, with deep expertise in accrual accounting and clinical trial financial management, including contracts and CRO oversight.

Proven leadership experience with a track record of building and developing high‑performing teams.

Advanced financial modeling and forecasting capabilities, including scenario planning and analysis.

Strong analytical, strategic thinking, and problem‑solving skills.

Excellent communication and interpersonal skills, with the ability to influence cross‑functional stakeholders and external partners.

Proficiency in financial systems and Microsoft Office Suite.

Preferred Experience

Experience supporting global clinical trials and managing financials across multiple currencies.

Experience with NetSuite, Zip, and Condor preferred.

Strong project management skills with the ability to manage multiple priorities in a fast‑paced environment.

Education

Bachelor’s degree in Finance, Accounting, or a related field required.

CPA or MBA preferred.

Travel Required:

Occasional travel may be required based on business‑needs.

Structure TherapeuticsInc. is anEqual-OpportunityEmployer.

Structure Therapeutics is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive. For this role, the anticipated base pay range is $205,000 - $250,000. The exact base pay offered for this role will depend on various factors, including but not limited to the candidate’s geography, qualifications, skills, and experience.

AtStructure, base pay is only one part of your total compensation package. The successful candidate will be eligible for an annual performance incentive bonus, new hire equity, and ongoing performance‑based equity. Structure Therapeutics also offers various benefits offerings, including, but not limited to, medical, dental, and vision insurance, 401k match, unlimited PTO, and a number of paid holidays including winter shutdown.

Fraud Alert

To all candidates: your personal information and online safety are a top priority for us.

Recruiters will always contact you using the domain of Structuretx.com. We will never request payments, ask for financial account information or sensitive information like social security numbers. If you are unsure if a message is from Structure Therapeutics, please email human resources.

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Worksite address

south san francisco, CA, 94083, US

Who can apply

Review the original listing for work authorization, qualifications and employer requirements.

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