Director, Commercial Excellence

Job description

Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people. Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence.

Summit’s team is inspired to touch and help change lives through Summit’s clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies, including:

Non-small Cell Lung Cancer (NSCLC)

HARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI.

HARMONi-3: Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.

HARMONi-7: Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC.

HARMONi-GI3: Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy.

Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.

Overview of Role:

The Director, CommercialExcellenceis a headquarters-based role within Summit Therapeutics Commercial Operations. This role owns the governance and execution layer of the Commercial Excellence function — incentive compensation administration, territory design and change management, CRM configuration and administration, targeting and segmentationmethodology, field reporting standards, and the national KPI framework. The Director reports to the Senior Director, Commercial Excellence and is the day-to-day operational counterpart to Marketing, Market Access, and Medical Affairs Operations,and Market Researchensuring every functionoperatesfrom a consistent, compliant, and well-governed infrastructure. This is a role for someone who thrives on building from scratch, can manage multiple workstreams simultaneously, and understands that operational excellence in oncology commercial launch is the foundation that makes field execution possible.

Role and Responsibilities:

Own incentive compensation design and administration — plan design, quota setting, goal crediting, dispute resolution, and payment accuracy across the full field organization

Own territory design and alignment — build andmaintainthe territory structure, manage alignment changes through a defined change governance process, andensure roster accuracy at all times

Own CRM configuration and administration — partner with IT and the Director of Commercial Data and Technology to configure,maintain, and continuously improve the CRM; own business requirements, user access, and data quality

Own targeting and segmentationmethodology— define andmaintainthe HCP and HCO targeting approach, manage decile assignments, and ensure targeting outputs are operationalized in the CRM and field tools

Define and govern national KPI standards —establishfield reporting definitions, maintain the national KPI framework, and ensure consistent measurement across all geographies

Serve as the operational counterpart to Marketing, Market Access, and Medical Affairs Operations — own the day-to-day working relationship with each function, ensure aligned processes, and resolve operational conflicts before they reach the field

Support Finance and Compliance on process governance, audit readiness, PDRP compliance, and Sunshine Act reporting requirements

Own roster management, sales crediting, and goal setting administration —maintainaccurateheadcount data, manage new hire and termination checklists, and ensure crediting rules are applied correctly

Partner with the Field Excellence team to ensure operational infrastructure is correctly translated into field-level intelligence — own the systems and processes that Field Excellence draws on to serve each sales leader

All other duties as assigned

Experience, Education and Specialized Knowledge and Skills:

Bachelor's degreerequired; advanced degree in business, life sciences, or a related field preferred

Minimum of 10+ years of relevant experience in the life sciences industry

Minimum5+years of experience in pharmaceutical or biotech commercial operations, with direct ownership of incentive compensation, territory alignment, or CRM administration

Oncology experience strongly preferred; buy-and-bill and biomarker-driven specialty experience a plus

Launch experiencerequired— must have experience building or inheriting a commercial operations infrastructure during a product launch, not simplymaintaininga running system

Deep working knowledge of Veeva CRM or equivalent; familiarity with IC administration platforms (Xactly, NICE/Varicent, or similar)required

Strong cross-functional collaboration skills — this role works daily with Marketing, Market Access,Market Research,Medical Affairs Operations, Finance, Compliance, and the Field Excellence team; the ability to resolve competing priorities without escalation is essential

High attention to detail and comfort with data — IC errors and territory misalignments have direct compliance, payroll, and field morale consequences; precision is not optional in this role

Travel up to 20% — primarily for national meetings, POA preparation, and field alignment activities

This is the pay for this position

Pay Transparency

$203,000 - $253,000 USD

Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.

Summit Therapeutics Inc.is an Equal Opportunity Employer and takes pride in creating and maintaining diverse environment. We do not discriminate in recruitment, hiring, training or promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Summit Therapeutics’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Voluntary Self-Identification of Disability

Form CC-305

Page 1 of 1

OMB Control Number

Expires 07/31/2029

Why are you being asked to complete this form?

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measureour progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at .

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

Alcohol or other substance use disorder (not currently using drugs illegally)

Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS

Blind or low vision

Cancer (past or present)

Cardiovascular or heart disease

Celiac disease

Cerebral palsy

Deaf or serious difficulty hearing

Diabetes

Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders

Epilepsy or other seizure disorder

Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome

Intellectual or developmental disability

Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD

Missing limbs or partially missing limbs

Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports

Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)

Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities

Partial or complete paralysis (any cause)

Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema

Short stature (dwarfism)

Traumatic brain injury

#J-18808-Ljbffr

Worksite address

princeton, NJ, 08543, US

Who can apply

Review the original listing for work authorization, qualifications and employer requirements.