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Job description
Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
Job Description
AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013, following separation from Abbott. AbbVie combines the focus and passion of a leading-edge biotech with theexpertiseand capabilities of a long-established pharmaceutical leader, to develop and market advanced therapies that address some of the world's most complex and serious diseases.AbbVie employs approximately50,000 people worldwide and markets medicines in more than 170 countries.
AbbVie Process Chemistry is responsible forthe chemical development of AbbVies clinical candidates. We areseekingexperiencedcandidatestoconduct process research and development ofdrug conjugatesfrom pre-clinical throughclinical development.
Job Description:
We are looking for a highly motivated person who canmake scientificcontributions across synthetic molecule modalities, with a focus on driving thedevelopment of drug-conjugateprogramsfrompreclinicaltolate-stagedevelopment. Roles and responsibilities will becommensuratewith experience and could range fromcontributions asanindividualmemberon project teamsdeveloping DrugSubstance processes to leading cross functional project teamsestablishingCMCprogram strategyforclinical assets.The candidate will lead in the development of conjugation chemistry as well as downstream unit operations culminating in drugsubstance. The candidate will serve as the chemistry representative on the Drug Substance team for drug-conjugate development programs and wouldbe responsible fordeveloping timelines and executing activities required for drugsubstance. Working with analytical and manufacturing colleagues, the candidate will develop productive collaborations and communications with scientific teams. The role may also have supervisory responsibilities focused on the mentoring and development of direct reportswhich may be working onaligned oralternate programs.
Responsibilities:
Thecandidate willparticipateonand/orlead activities associated withprocess development andcharacterization for newdrugconjugates.
Develop and characterizedrug-conjugate(and other modalities) processes in the laboratory and translate them to scalable processes.
Participateonand/orleadproject teams toenable CMCdeliverables(materials,methods,milestones).
Authorand review key regulatory documents, laboratory data, technicalreportsandinternal/external presentations and publications.
The position involves multi-disciplinary interactions with organic chemists, analytical chemists, engineers, drug product development, and program management. The selectedcandidate will collaborate withand/orleadcross-functionalCMC teamsto advancepre-clinical andclinical candidates.
The candidate will understand and adhere to corporate standardsregardingcode of conduct,safetyand GXP compliance.
The candidate maysuperviseone or moredirectreportsthat may beassociated withotherprograms but befullyresponsiblefortheirmentorshipandcareerdevelopment.
Qualifications
MinimallyBS(12+ years); MS (10+ years) or PhD (4+ years) in Chemistryor allied field,with2+ years ofpreviouswork experience in a pharmaceutical laboratory setting.
Experience indrug-conjugateprocess developmentisarequirement.
Proven scientific leadership; strong interpersonal and communication skills forfacilitatingcollaborations and a demonstrated ability to lead cross-functional process development teams.
The successful candidate will have a strong understanding of modern organic chemistry, mechanistic theory, control strategy development, and regulatory starting material strategies.
Additional Information
Multiple times, we have been globally recognized as a "Great Place to Work" and we are proud to provide our employees with the flexibility to maintain a healthy work-life balance. We take our impact on the environment and our communities seriously and therefore focus on giving something back on a regular basis. We are committed to equality, equity, diversity and inclusion (EED&I) a commitment that is fundamental to us. This includes appreciating different perspectives, creating an inclusive culture and treating all employees with dignity and respect.
At AbbVie, your individual contributions count help us move mountains together. Be a part of our success, grow with us and accomplish more than you could have imagined. Sounds like the perfect career opportunity for you? We look forward to receiving your application! All you need is a complete CV we will discuss everything else with you.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.
Equal Opportunity Employer/Veterans/Disabled.
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Worksite address
north chicago, IL, 60086, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.