Head of Pharmacogenomics (PGx)

Job description

Who We Are & What We Do

At Helix, our mission is simple: to help everyone improve their lives through their DNA.

Ready to make a real-world impact with your skills? At Helix, we're transforming healthcare by making genomics a standard of care. We partner with health systems and life science companies to accelerate the integration of genomic data into clinical practice. Join us in building a future where healthcare is personalized, proactive, and powered by genomics.

As the business leader for pharmacogenomics at Helix, you’ll define what we build, how our solutions are put into practice, and how the PGx business grows. Working across Commercial, Product, Medical, and Operations, you’ll shape our go-to-market strategy, influence the product roadmap, and engage directly with health-system and health-plan leaders to turn PGx capabilities into products and partnerships that improve care and lower the cost of care.

Why this role is different

Shape the future of PGx adoption: Helix’s Sequence Once, Query Often® model makes genomic insights available on demand at the point of care. You’ll build on that advantage to define how health systems and health plans use PGx to inform medication decisions, and create the products and partnerships that make PGx a standard part of patient care

A builder’s mandate: You’ll have the opportunity to shape a growing business from the ground up, with a direct connection between customer needs, product decisions, commercial strategy, and clinical adoption

Find and Build High-Value PGx Use Cases: Working closely with customers, you’ll identify patient populations where PGx can improve care and lower total cost of care, then turn those opportunities into compelling value propositions and scalable rollout plans

As Head of Pharmacogenomics at Helix, you will:

Own the PGx business mandate: Set the growth strategy for Helix’s PGx business, with accountability for product adoption and customer engagement across health systems and health plans

Develop compelling PGx ROI models: Inform the design of ROI models that demonstrate the economic value of PGx across fee-for-service and risk-bearing organizations

Serve as the external subject matter expert: Represent Helix in conversations with health system and health plan executives, pharmacy leaders, and clinical teams to design and deploy enterprise PGx programs

Shape the product roadmap: Translate customer and clinical needs into product priorities, including EHR-embedded Clinical Decision Support, patient identification, drug-gene interaction alerting, and pharmacist workflows

Build the go-to-market motion: Partner with Marketing and Business Development to define target customers, sharpen the Helix PGx value proposition, and create the materials and commercial strategies that turn interest into adoption

Inform strategy through clinical and market Insight: Track evolving clinical guidelines,, reimbursement trends, and developments in PGx to identify new product and commercial opportunities

About you

7+ years of experience in pharmacogenomics, precision medicine, clinical digital health, or a related product or commercial role, ideally at a PGx or precision medicine company

Experience leading complex enterprise conversations with health system or health plan executives and building a clear clinical and economic case for adoption

Strong understanding of EHR integration, clinical decision support, and physician and pharmacist workflows

Ability to translate customer and clinical needs into product priorities and commercial strategies

Clear, credible communicator who can work effectively across clinical, commercial, product, and technical teams

AI tools are a natural part of how you work – to synthesize clinical literature, model ROI scenarios, and move faster on customer deliverables

The ideal candidate will have:

PharmD, MD, or advanced degree in a relevant clinical, scientific, or health related field

Experience in health system pharmacy, comprehensive medication management, or clinical decision support

Experience developing health economic models, ROI cases, reimbursement strategies, or value-based commercial arrangements

Expected Interview Process:

1) Recruiter Screen2) Manager Screen/Tech Screen3)Onsite4)Offer

Expected Pay For This Role:

There are 3 distinct parts to your Helix offer:1)Base Salary2)Annual Bonus3)Equity

Expected Helix Base: $206,000 - $265,000

Expected Helix Discretionary Annual Bonus: 20% of your annual salary

Equity: We offer generous equity at Helix. If you receive a Helix offer your recruiter will book dedicated time with you to educate you on our equity model.

Aside from working alongside brilliant, dedicated, passionate, down-to-earth, curious, warm, and thoughtful people, we also provide great benefits:

Comprehensive Health Insurance with Date of Hire eligibilityAbove average employer paid premium coverage

12 weeks Helix Paid Parental Leave option

401(k) with employer matching of up to 3% and 100% Vesting on the Date of Hire

Comprehensive Well-Being Benefits

Flexible PTO

Remote options for many roles and a home office stipend

What To Expect During Your First 90 days:

First 30 days:you’ll spend time learning the Helix way, completing training and onboarding for your roles, and getting introduced to your team and relevant stakeholders. You’ll also gain a deeper understanding of our customers, our products, the impact we make in the lives of our communities, and how to thrive at Helix through participation in Helix U.

Day 30 - 60:you’ll spend time contributing to projects, deeply familiarizing yourself with team and company processes, and developing a deeper understanding of Helix’s products, services and capabilities.

Day 60 - 90:you’ll build your OKRs with your manager, start to take ownership of projects and initiatives on your team, and begin to demonstrate your impact on the Helix mission.

To learn how Helix collects, uses, and protects your personal information during the recruitment process, please review our Privacy Notice.

Helix is proud to be an equal opportunity employer, and committed to providing employment opportunities regardless of race, religious creed, color, national origin, ancestry, physical disability, mental disability, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, pregnancy, childbirth and breastfeeding, age, sexual orientation, military or veteran status, or any other protected classification, in accordance with applicable federal, state, and local laws.

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Who can apply

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