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Job description
Job Description
Role Summary
The High Throughput Human Biology group is seeking a highly motivated Research Scientist to support discovery programs through the development and implementation of innovative human biology assays. Working in a collaborative, multidisciplinary environment, the successful candidate will draw on expertise in cellular and molecular biology, laboratory automation, and data analysis to develop in vitro assays spanning multiple levels of biological complexity and define their application within high-throughput screening strategies. The successful candidate will also evaluate and incorporate emerging technologies, establish scalable experimental workflows, and partner across disciplines to translate scientific needs into robust solutions. They will leverage AI-enabled tools to improve workflow efficiency, accelerate experimental iteration, and support data-driven project decisions.
The ideal candidate will bring strong hands-on laboratory skills, scientific and technical creativity, and the ability to independently advance projects from concept through implementation.
Key Responsibilities
Develop, optimize, and implement high-throughput human biology assays to address key questions or challenges in discovery biology across multiple programs
Build integrated automation workflows for cellular and biochemical assays leveraging robotics, high-throughput liquid handling, and custom computational solutions
Execute screening and follow-up studies, analyze complex datasets, and translate findings into actionable recommendations for project teams
Troubleshoot assay and automation performance and drive continuous improvements in throughput, data quality, and operational reliability
Identify unmet scientific needs relevant to our research areas and develop solutions from conceptualization through prototyping and implementation
Evaluate emerging technologies and apply promising solutions to internal programs
Represent the High Throughput Human Biology group as part of highly collaborative, interdisciplinary teams, communicate results clearly and maintain rigorous, reproducible records
Required Qualifications
PhD in a relevant scientific discipline with 0-3 years of relevant experience
Scientifically curious, driven and independent, motivated by making impact to project progression
Demonstrated creativity in biological assay development
Foundational molecular biology and cell biology laboratory experience in multi-well plate formats, including complex human cellular assays, immunoassays, qPCR, high-content imaging, and other relevant functional and target engagement assays
Proficiency in relevant coding languages, such as Python, R or MATLAB
Proven track record of success working in collaborative, multi-disciplinary teams
Excellent written and verbal communication skills
Preferred Qualifications
Hands-on experience with laboratory automation, automated liquid handling, or integrated instrumentation strongly preferred
Experience developing or deploying AI-enabled scientific and computational workflows strongly preferred
A record of building and applying useful tools, prototypes, methods, or process improvements
Ability to multi-task and prioritize effectively across involvement in multiple projects
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range
$105,600 - $158,400
Disclosure Statement
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation
On-Site Designated
Flex Eligibility Status
In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and ma
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Worksite address
boston, MA, 02298, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.