About this opportunity
Breakout Ventures lists this Histology Manager opportunity in san francisco, California. Review the employer’s description below for duties, qualifications and application requirements.
Job description
THE OPPORTUNITY
We are seeking an experienced Histology Manager to lead our histology operations and team. This role will be responsible for ensuring consistent, high-quality, and timely preparation of tissue samples supporting an evolving range of research and data generation workflows.
This role combines deep technical expertise in histology with strong operational and people leadership. This role will oversee day-to-day histology operations, develop and mentor the histology team, establish and maintain high quality standards, and continuously improve laboratory workflows with an eye for automation as our sample volumes and technical capabilities scale.
ROLE AND RESPONSIBILITIES
The Histology Manager will work closely with colleagues across Biosample Operations, Pathology, Platform Innovation, Engineering, and other functions. The ideal candidate is an experienced histotechnologist who excels at building high performing teams, solving difficult tissue processing and sectioning problems, and developing robust laboratory operations in a fast-paced and dynamic environment. Success in this role will require a determination to push the boundaries of histology operations to creatively scale workflows.
Responsibilities include:
Histology operations and technical leadership
Lead day-to-day histology operations, including FFPE reembedding, sectioning, H&E staining, and related tissue processing workflows
Serve as technical resource for difficult or complex histology issues
Establish and maintain standards for each step of the histology workflow, troubleshoot all aspects of the histology workflow, lead root cause investigations where appropriate
Ensure consistent production of high quality tissue sections for downstream assays including H&E, immunostaining, and spatial transcriptomics
Partner with downstream assay teams to understand requirements and ensure appropriate tissue preparation
Communicate capacity constraints, technical risks, and sample quality issues to stakeholders
Evaluate and implement new histology equipment, consumables, technologies, workflows, and cutting edge automation to enable histology operations at scale
Team leadership
Manage, mentor, and develop the histology team
Establish clear expectations for technical performance, quality, productivity, and laboratory procedures
Provide regular feedback, coaching, and career development for team members
Develop onboarding and training programs for new histology team members
Foster a collaborative, quality-focused, and continuous-improvement culture
REQUIRED EDUCATION & EXPERIENCE
Bachelor’s degree in biological sciences, histotechnology, or related field
Extensive hands-on experience in histology, including FFPE tissue preparation and sectioning
Demonstrated expertise sectioning a broad range of human tissue types, including challenging specimens
Strong understanding of common histology workflows and artifacts, including tissue microarrays, with ability to troubleshoot complex issues
Experience managing a histology team supporting high throughput tissue workflows
Experience managing laboratory workflows, priorities, and capacity, including working with laboratory information management systems
Strong organizational skills and attention to detail, particularly when working with high value or limited tissue samples
QUALIFICATIONS AND SKILLS
Strong track record in exceeding expectations, with a drive for efficiency
Demonstrated ability to work effectively in a fast paced, highly collaborative and dynamic environment
Strong written and verbal communication skills
Team player, eager to unblock bottlenecked steps and lead continuous process improvement
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Worksite address
san francisco, CA, 94199, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.