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RXinsider LTD.

Immunoassay Development Scientist - Analyte Detection

fremont, CA

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About this opportunity

RXinsider LTD. lists this Immunoassay Development Scientist - Analyte Detection opportunity in fremont, California. Review the employer’s description below for duties, qualifications and application requirements.

Job description

Become your most extraordinary self! Our team is intensely proud to be a major provider of services and products to the drug discovery research industry. Join Eurofins DiscoverX Products, LLC part of the Eurofins Discovery group of companies serving global clients in the Pharma and Biotech industries. Work alongside industry experts and collaborate with team members to directly and positively impact human health worldwide!

We have a philosophy to support work life balance, career progression opportunities and offer many benefits such as formal mentoring programs, tuition reimbursement, extensive career training programs, competitive health benefits, paid time off and 10 annual paid holidays*.

Job Description

We are seeking for hands‑on immunoassay developers for a new Analyte Detection Business Unit. If you have designed assays from scratch, selected and screened reagent pairs, and solved real development problems across ELISA, MSD, TR‑FRET, AlphaLISA, or related formats, we want to hear from you. Here’s what you’ll do:

Laboratory Execution & Technical Support

Design and execute bioconjugation strategies for labeling antibodies and other proteins with donor/acceptor fluorophores (NHS‑ester, maleimide, and related chemistries); optimize reaction conditions, purification, and labeling efficiency from first principles

Develop homogeneous immunoassays (TR‑FRET, HTRF, AlphaLISA, MSD, and/or ELISA) for analyte detection; own the full development cycle from reagent selection and antibody pairing through format optimization and matrix validation

Lead independent antibody screening campaigns to identify optimal capture/detection pairs; apply structured DOE approaches to optimize reagent concentrations, buffer formulations, and assay window

Conduct routine assay validation experiments, including precision, accuracy, linearity, and range determination

Prepare biological samples, reagents, and buffers according to SOPs

Operate and maintain laboratory equipment, including plate readers, liquid handlers, and analytical instruments

Independently diagnose and resolve assay performance failures; apply root‑cause analysis to reagent, buffer, and instrument variables and propose data‑driven corrective actions

Support antibody screening and characterization activities

Assist with benchmarking studies comparing assay performance to competitor products

Data Management & Documentation

Maintain detailed, accurate, and organized laboratory notebooks documenting all experimental procedures and observations

Analyze experimental data using GraphPad Prism, Excel, or similar software

Generate clear data summaries, graphs, and tables for internal reports and presentations

Contribute to technical reports and validation documents

Assist in drafting sections of SOPs and user manual protocols

Ensure all documentation meets company quality standards and regulatory requirements

Collaboration & Learning

Work collaboratively with Senior Scientist and other team members to support project timelines

Participate in team meetings and provide updates on experimental progress

Communicate experimental results and technical challenges effectively to the supervisor

Actively seek learning opportunities to develop technical skills in bioconjugation and immunoassay development

Support cross‑functional activities with Manufacturing, Quality, and Marketing teams as needed

Participate in training programs to enhance scientific and professional development

Compliance & Safety

Adhere to all site employee health and safety (EHS) and IT security requirements

Demonstrate and promote the company vision and values

Maintain regular attendance and punctuality

Conduct all activities in a safe and efficient manner

Perform other duties as assigned

Meet project deadlines and adjust work hours as needed to support team objectives

Qualifications

Here is who and what we are are looking for in the ideal candidate:

Education/Experience (BMQ)

BS/MS in chemistry, biochemistry, biology, or related discipline with 3–7 years of hands‑on industrial experience developing immunoassays from scratch (ELISA, MSD, TR‑FRET/HTRF, AlphaLISA, or equivalent); experience must include reagent selection, antibody screening, and quantitative assay optimization — not solely protocol execution

Demonstrated experience independently developing and validating immunoassays — including reagent pair selection, signal‑to‑noise optimization, and characterization studies — with a verifiable track record of assays taken from concept to validated format

Solid understanding of antibody‑antigen binding kinetics, epitope considerations for sandwich vs. competitive immunoassay design, and the impact of protein biochemistry on assay performance

Familiarity with aseptic technique and cell culture is a plus

Ability and/or Skills (BMQ)

Strong laboratory skills with attention to detail and accuracy

Basic proficiency in data analysis using Excel; familiarity with GraphPad Prism or similar software is a plus

Good organizational and time management skills with the ability to balance multiple tasks

Ability to design experiments from first principles, generate and test hypotheses, and translate results into actionable next steps — not limited to following pre‑written protocols

Strong work ethic with demonstrated reliability and accountability

Eagerness to learn new techniques and acquire new scientific knowledge

Good verbal and written communication skills

Team player with positive attitude and willingness to collaborate

Ability to work independently on assigned tasks while knowing when to seek guidance

Comfortable working in a fast‑paced laboratory environment with defined deadlines

Additional Preferences

Experience developing assays in two or more immunoassay platforms (e.g., ELISA, MSD/ECL, TR‑FRET/HTRF, AlphaLISA, Luminex); cross‑platform familiarity is a strong differentiator

Hands‑on bioconjugation experience beyond kit use: NHS‑ester, maleimide, aldehyde, or click‑chemistry conjugation of small molecules, haptens, or fluorophores to antibodies or proteins, including optimization of degree of labeling (DOL) and purification

Hands‑on experience with multi‑channel pipettes, automated liquid handlers, and plate readers

Familiarity with time‑resolved fluorescence or FRET‑based detection principles (TR‑FRET/HTRF, LANCE, or AlphaLISA); experience with plate reader instrumentation for fluorescence or luminescence readouts (e.g., PHERAstar, EnVision, or equivalent)

Academic or industrial research experience in drug discovery, diagnostics, or related areas

Experience maintaining detailed laboratory notebooks and documentation

Applied experience with Design of Experiments (DOE) for reagent concentration and buffer optimization, not merely theoretical familiarity

Experience presenting research findings in laboratory meetings or scientific conferences

Demonstrated problem‑solving skills and scientific curiosity

Proficiency with Microsoft Office Suite (Word, Excel, PowerPoint)

Additional Information

Salary Range: $95,000 - $125,000/yr.

Excellent full time benefits including comprehensive medical coverage, dental, and vision options

Life and disability insurance

401(k) with company match

Paid vacation and holidays

Eurofins USA Discovery Services is a Disabled and Veteran Equal Employment Opportunity employer.

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Worksite address

fremont, CA, 94537, US

Who can apply

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