About this opportunity
IDEAYA Biosciences, Inc. lists this Medical Director, Drug Safety and Pharmacovigilance opportunity in south san francisco, California. Review the employer’s description below for duties, qualifications and application requirements.
Job description
Job Summary About IDEAYA Biosciences:
IDEAYA is a precision medicine oncology company committed to the discovery, development, and commercialization of transformative therapies for cancer. Our approach integrates expertise in small‑molecule drug discovery, structural biology and bioinformatics with robust internal capabilities in identifying and validating translational biomarkers to develop tailored, potentially first‑in‑class targeted therapies aligned to the genetic drivers of disease. We have built a deep pipeline of product candidates focused on synthetic lethality and antibody‑drug conjugates, or ADCs, for molecularly defined solid tumor indications. Our mission is to bring forth the next wave of precision oncology therapies that are more selective, more effective, and deeply personalized with the goal of altering the course of disease and improving clinical outcomes for patients with cancer.
When you're at IDEAYA, you will be in the midst of brilliant minds working on precision medicine therapies to help cancer patients. We are passionate and committed about being at the forefront of oncology medicine, which means we all have a high internal drive that is at the very core of every person at IDEAYA. We are inquisitive, ask deep questions, and are data‑driven innovators who like to collaborate and use team work to move science forward.
Location:
South San Francisco
Position Summary:
We are seeking an experienced Medical Director of Patient Safety and Pharmacovigilance to join IDEAYA. The Medical Director, Medical Safety – ICSR provides medical leadership and clinical oversight for Individual Case Safety Report (ICSR) activities across the company’s global pharmacovigilance program. This role is primarily responsible for high‑quality medical review of safety cases and serves as the key medical interface with the company’s pharmacovigilance vendor for day‑to‑day case processing activities. The role partners closely with Safety Operations, who shares responsibility for vendor oversight related to case processing, quality, and compliance. Together, they ensure timely, consistent, and inspection‑ready safety reporting in a growing organization. This position is based in our South San Francisco headquarters offices and required to be onsite four days per week per our company policy. Reporting to: Senior Medical Director, Patient Safety & Pharmacovigilance.
What you’ll do:
Serve as the primary medical expert who performs and overlooks medical review of ICSR, including complex, and medically significant cases in the oncology therapeutic area
Provide clinical assessment of adverse events, including causality, seriousness, expectedness, and review narrative content for clinical accuracy and flow
Act as the primary medical point of contact for the pharmacovigilance vendor for day‑to‑day ICSR‑related questions and escalation
Provide medical input into vendor oversight activities, including case quality review, accuracy of triage, and regulatory submission compliance
Support development of medical review guidelines, training materials, and vendor‑facing instructions
Collaborate closely with the IDEAYA Safety Operations team to ensure quality across global case processing activities by monitoring quality metrics and address non‑compliance events
Conduct and oversee thorough investigations of quality events, deviations and CAPAs pertaining to case processing and regulatory compliance
Support development, implementation and tracking of CAPAs
Participate in vendor governance meetings as the medical representative
Support regulatory inspections, audits, and health authority inquiries related to ICSR processing and medical review
Contribute to the development and maintenance of SOPs and work instructions related to medical case review
Serve as the medical safety point of contact for any assigned molecule(s)
Provide safety input for aggregate safety reports, protocol amendments, investigator’s brochure, informed consent and other key regulatory safety documents
Partner with Safety Science, Regulatory Affairs, and Clinical teams as needed on safety issues requiring medical input
Requirements:
MD (or equivalent international medical degree) with 2+ years of bedside clinical experience
5–8+ years of oncology experience in drug safety/pharmacovigilance
Strong hands‑on ICSR medical review experience
Demonstrated experience working with external PV vendors or CROs
Solid knowledge of global PV regulations (FDA, EMA, ICH)
Strong medical judgment, attention to detail, and ability to work effectively in a matrix environment
Total Rewards:
Along with our inspiring mission, and highly collaborative and inclusive environment, IDEAYA offers a competitive total rewards package that reflects our pay‑for‑performance philosophy where employees are eligible to be considered for merit‑based salary increases, company discretionary short‑term incentive plan participation, and company discretionary stock option awards (based on board approval).
Our comprehensive benefits package includes, but is not limited to, medical/dental/vision coverage (100% company paid for employees and 90% company paid for dependents), 401k, ESPP, and wellness programs.
medical/dental/vision coverage (100% company paid for employees and 90% company paid for dependents)
401k
ESPP
wellness programs
The expected salary range for the role of Medical Director, Drug Safety and Pharmacovigilance is $268,000 - $331,000.
This position requires you to work onsite in the office at the Company’s facilities for training & meetings, with work‑from‑home flexibility, and the Company requires that all employees working in its facilities be fully vaccinated (except as required by applicable law). Therefore, this position requires you to be fully vaccinated from COVID‑19, subject to reasonable accommodations for medical or religious reasons, and/or as otherwise required by applicable law. The Company considers you fully vaccinated once 14 days have passed since you received either the second dose in a two‑dose COVID‑19 vaccine series or a single‑dose COVID‑19 vaccine. The vaccine must have been FDA approved, have emergency use authorization from the FDA, or, for persons fully vaccinated outside of the U.S., be listed for emergency use by the World Health Organization.
All employees are expected to act with integrity and in full compliance with applicable laws, regulations, and IDEAYA policies, including IDEAYA’s Code of Conduct. Employees must demonstrate good judgement and ethical behavior in all business activities, maintain patient and product safety as a top priority, and report any suspected violations of law or Company policy through appropriate channels.
The Company complies with all laws respecting equal employment opportunities and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law. This position requires you to work onsite in the office at the Company’s facilities for training & meetings, with work‑from‑home flexibility, and the Company requires that all employees working in its facilities be fully vaccinated (except as required by applicable law).
IDEAYA is an equal opportunity employer. In accordance with applicable law, IDEAYA does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets.
We are committed to providing reasonable accommodations to qualified individuals with disabilities. If you need assistance or an accommodation due to a disability, please get in touch with us at
At IDEAYA we believe in the importance of on‑site presence by all team members as an essential ingredient to effective collaboration. Our hybrid approach to work at IDEAYA includes all staff being on‑site four days per week in the office, and one day per week working from home.
IDEAYA Company Values:
Passionate Commitment Fearless Innovation Courageous Integrity Respectful Teamwork Objective Decision‑Making Empowered Accountability
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Worksite address
south san francisco, CA, 94083, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.