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Job description
Posting Number
STA00724PO26
Job Family
Research
Job Function
Research Laboratory Management
USC Market Title
Research Laboratory Manager
Link to USC Market Title
Job Level
R2 - Research
Business Title (Internal Title)
Organoid and Biofabrication Core Manager
Campus
Columbia
Work County
Richland
College/Division
Office of Research
Department
OOR Research Cores
State Pay Range
Unclassified
USC Market Range
MRK - $86,515 $110,307 $134,098
Anticipated Hiring Range
$86,5150-$100,000
Part/Full Time
Full Time
Hours per Week
37.5
Work Schedule
Standard working schedule: 8:30am – 5:00pm
Must be willing to work a flexible schedule to meet the needs of the department.
Basis
12 months
Job Search Category
Other Professional
About University of South Carolina
From the Upstate to the Lowcountry, the University of South Carolina system is transforming the lives of South Carolinians through the impact of our eight institutions and 20 locations throughout the state. More than 50,000 students are enrolled at one of eight institutions, including the research campus in Columbia and comprehensive four-year universities in Aiken, Upstate and Beaufort. In addition, our Palmetto College campuses in Salkehatchie, Union, Lancaster and Sumter enable students to earn associate or bachelor’s degrees through a combination of in-person, online or blended learning. All of our system institutions place strong emphasis on service — helping to build healthier, more educated communities in South Carolina and beyond.
Veterans' Preference Statement
The University of South Carolina is committed to equal opportunity and proudly values the skills and experience military veterans bring to our workforce. Across South Carolina, we are making veterans a priority for employment and recognize their vital contributions to our state and our communities.
Advertised Job Summary
The University of South Carolina is seeking to hire a Core Manager to provide scientific and operational leadership for the Organoid and Biofabrication Core, a division of the Instrumentation Resource Facility (IRF) within the Office of the Vice President for Research. The Core will provide fee-for-service, collaborative research support, and instrument access for organoid models, induced pluripotent stem cell (iPSC)-based models, tissue engineering, bioprinting, and related biofabrication applications.
The Core Manager will lead the day-to-day scientific and operational activities of the division and will work directly with investigators to translate research questions into practical, reproducible experimental workflows. A central responsibility of the position is understanding and integrating both upstream and downstream processing for advanced cell-based models, including mammalian cell culture, cell expansion and differentiation, organoid and iPSC workflows, biofabrication, sample preparation, phenotypic characterization, flow cytometry, fluorescence microscopy, and quantitative analysis. The Manager will collaborate with other IRF divisions and institutional partners to connect these technologies into comprehensive research workflows.
Job Related Minimum Required Education and Experience
Requires a Doctoral (Ph.D.) degree in area of research specialty.
Preferred Qualifications
Doctoral degree in cell biology, molecular biology, biomedical engineering, bioengineering, biotechnology, stem cell biology, tissue engineering, or a closely related discipline.
Demonstrated hands-on experience with mammalian cell culture and advanced cell-based research models, including organoids, stem cells/iPSCs, tissue engineering, and/or biofabrication.
Experience with bioprinting or a closely related biofabrication technology.
Demonstrated ability to independently develop, optimize, troubleshoot, and document biological or bioengineering protocols.
Demonstrated knowledge of upstream and downstream processing for advanced cell-based models, with working knowledge of flow cytometry and microscopy as complementary characterization methods.
Experience with human iPSC culture and differentiation, organoid model development, and/or other advanced three-dimensional cell culture systems.
Experience with bioprinting, tissue engineering, biomaterials, bioinks, or related biofabrication technologies.
Experience applying flow cytometry, fluorescence/confocal microscopy, image analysis, or other analytical methods to characterize cells, organoids, or engineered tissues.
Experience working in a centralized research core, shared-resource facility, or multidisciplinary research environment, including development and implementation of new research services or standardized workflows.
Knowledge/Skills/Abilities
Working knowledge of mammalian cell culture, aseptic technique, cell expansion, cryopreservation, and organoid and stem cell/iPSC model systems, including their differentiation, maintenance, and experimental use.
Knowledge of tissue engineering and bioprinting/biofabrication workflows, including biomaterials and bioinks, construct handling, post-fabrication culture, and troubleshooting.
Demonstrated understanding of integrated upstream and downstream workflows for advanced cell-based models, with working knowledge of flow cytometry and fluorescence/confocal microscopy for sample preparation, characterization, imaging, analysis, and interpretation.
Ability to develop, optimize, validate, standardize, document, and troubleshoot complex biological protocols and shared-resource services, including quality assurance, quality control, reproducibility, and SOP development.
Ability to assess experimental feasibility, recognize technical limitations, recommend appropriate workflows or complementary analytical approaches, and train users with varying levels of technical expertise.
Strong communication, collaboration, organizational, and administrative skills sufficient to work with investigators, technical staff, vendors, and institutional stakeholders while managing service requests, scheduling, documentation, and concurrent projects.
Ability to create iPSCs from somatic cells.
Scientific and Operational Leadership
Direct the day-to-day operations of the Organoid and Biofabrication Core. Maintain operational readiness of cell-culture and biofabrication spaces; oversee biofabrication and organoid performance, preventive maintenance, troubleshooting, and repair in coordination with vendor technical support; maintain appropriate supplies and inventories; establish and monitor quality-control practices; and support compliance with applicable institutional safety and laboratory requirements.
Essential Function: Yes
Percentage of Time: 25
User Consultation, Training, and Integrated Research Support
Consult with internal and external investigators on experimental design, feasibility, sample requirements, and appropriate use of Core technologies. Train users in relevant organoid, iPSC, cell-culture, tissue-engineering, and biofabrication workflows. Provide scientific troubleshooting and help investigators integrate upstream culture and fabrication processes with downstream characterization approaches, including flow cytometry, fluorescence microscopy, image analysis, and related analytical methods.
Essential Function: Yes
Percentage of Time: 20
Protocol, Model, and Service Development
Develop, optimize, validate, document, and implement new organoid, iPSC, tissue-engineering, bioprinting, and biofabrication protocols and services. Establish standardized workflows, acceptance criteria, quality-control measures, and reproducibility standards. Adapt research protocols for reliable use in a shared-resource environment and evaluate emerging technologies, models, biomaterials, and applications that may expand the Core’s service portfolio.
Essential Function: Yes
Percentage of Time: 40
Core Administration and Service Management
Use Agilent iLab and other institutional systems to review and approve service requests, manage equipment and service access, support scheduling and billing workflows, maintain service documentation, and monitor usage and operational metrics. Assist the IRF Director with service costing, reporting, planning, and other administrative activities related to the division.
Essential Function: Yes
Percentage of Time: 15
Safety Sensitive or Security Sensitive
No
Hazardous weather category
Non-Essential
Number of Vacancies
1
Job Open Date
09/25/2026
Job Close Date
10/02/2026
Open Until Filled
No
Special Instructions to Applicant
Please ensure that the cover letter provides details on your experience with 3D cell and tissue culture, cell sorting, and fluorescence cell imaging.
We are only accepting applications submitted by October 2, 2026.
Health and Life Insurance
Retirement Programs
Paid Tuition
Dependent Scholarships
Annual Leave
Sick Leave
13 Paid Holidays (including an extended December holiday)
Paid Parental Leave
Professional Development Opportunities
EEO Statement
The University of South Carolina does not discriminate in employment opportunities or decisions for qualified persons on the basis of age, ancestry, citizenship status, color, disability, ethnicity, familial status, gender, gender identity or expression, genetic information, military status, national origin, pregnancy, race, religion, sex, sexual orientation, veteran status, or any other protected category under applicable law.
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Worksite address
columbia, SC, 29228, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.