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Scorpion Therapeutics

Post-Doctoral Scientist - Technical Services and Manufacturing Science

indianapolis, IN

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Job description

Post-Doctoral Scientists at Lilly are responsible for:

Ensuring reliability of manufacturing systems

Searching for and implementing continuous improvements

Driving technical projects

Maintaining processes in compliance with US and global regulations

Designing and developing drug processes and delivery systems

The position provides technical and scientific support for development of commercial processes (synthesis and purification) for biomolecules including proteins, peptides, and oligonucleotides. Responsibilities include designing and executing experiments to advance process knowledge, process optimization, and production technical transfer.

Key objectives/deliverables:

Understand scientific principles for manufacturing intermediates, drug substances, and drug products (chemistry and equipment interaction)

Understand chemistry and stability of small molecules, peptides, and/or biomolecules

Develop laboratory-scale models for key synthesis/purification steps

Design, conduct, and analyze statistically designed experiments to optimize processing conditions

Understand scale-up requirements and partner with pilot plant as needed

Provide technical support for process development areas

Write and document work appropriately

Mentor lab associates

Participate in technology transfer as needed

Work independently and collaboratively

Basic requirements:

Ph.D. in Biochemistry, Biology, Molecular Biology, Pharmacology, Chemistry, or related fields

Demonstrated experience in protein, oligonucleotide, and peptide chemistry and/or purification

Record of publications in peer-reviewed journals and presentations/posters at scientific conferences

Additional information:

Fixed duration: two years with potential to extend to 3 years; up to 4 years total; opportunities to apply for full-time roles afterward

Location: Indianapolis, IN

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Worksite address

indianapolis, IN, 46262, US

Who can apply

Review the original listing for work authorization, qualifications and employer requirements.

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