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Job description
Principal Clinical Scientist (AI Training)
About the Role
What if your years of clinical trial expertise could directly shape how AI reasons about medical evidence, regulatory submissions, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to cutting-edge AI research - ensuring the clinical data and analyses powering next-generation AI systems meet the standards expected in real-world regulatory environments.
This is a fully remote, flexible contract role built for experienced clinical scientists who want to work at the intersection of medicine and frontier technology. No AI background needed - just deep expertise in clinical research and regulatory science.
Organization
: Alignerr
Type
: Hourly Contract
Location
: Remote
Commitment
: 10-40 hours/week
What You'll Do Design and review clinical trial protocols used to generate high-quality, regulator-ready training datasets for AI systems
Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations
Provide expert, structured feedback that directly improves how AI models reason about clinical trial data, endpoints, and outcomes
Work independently and asynchronously - fully on your own schedule
Who You Are Senior-level experience designing clinical trial protocols for regulatory submission
Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent regulatory bodies
Strong background in clinical research methodology, biostatistics, or translational science
Naturally detail-oriented with a systematic, rigorous approach to scientific evaluation
Clear and precise written communicator comfortable providing structured, actionable feedback
Nice to Have Prior experience with data annotation, data quality assurance, or evaluation systems
Familiarity with AI tools or machine learning workflows in clinical or biomedical contexts
Background in pharmacovigilance, medical affairs, or health technology assessment
Experience working across multiple therapeutic areas or global regulatory jurisdictions
Why Join Us Work directly on frontier AI systems making a real impact on clinical and biomedical research
Fully remote and flexible - work when and where it suits you
Freelance autonomy with the structure of meaningful, high-stakes scientific work
Influence how AI understands, evaluates, and communicates real-world clinical evidence
Collaborate with leading AI research teams and labs at the cutting edge of the field
Potential for ongoing work and contract extension as new projects launch
Worksite address
new york, NY, 10261, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.