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Astera Cancer Care

Principal Investigator

city of albany, NY

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Job description

Why Join Us?

Be part of a practice at the forefront of cutting‑edge cancer care and advanced treatments Access opportunities for professional growth and continuing education. Work alongside a collaborative and compassionate team of experts dedicated to making a difference. Enjoy the convenience of multiple locations throughout the Capital Region. Contribute to groundbreaking clinical trials that shape the future of oncology care. Discover your career potential with a practice dedicated to excellence and innovation.

Job Description:

Reporting Relationship

The Launch PI works closely with site Clinical Operations leadership, the Director of Nursing Services, START Executive Leadership, the Chief Medical Officer, and Technology leadership. The Launch PI is accountable for physician investigator activity at the site until a full‑time Physician Investigator Site Leader assumes that responsibility, at which point the Launch PI may transition to a defined ongoing role or complete the engagement.

Engagement Model and Time Commitment

Pre-Launch (Months 2–3 before go‑live): a few hours per week, focused on protocol and study selection input, credentialing, regulatory and IRB set‑up, and early staff engagement.

Final Month Before Go‑Live: time commitment increases to approximately 16 hours per week.

Includes an on‑site visit of up to one week at an established NYOH/START clinic to become familiar with START systems, workflows, and documentation standards.

Go‑Live and Early Operations: continues at approximately 16 hours per week as the site’s Principal Investigator, providing patient‑facing and protocol oversight through the early operational period.

Transition: upon hire of a full‑time Physician Investigator Site Leader, the Launch PI typically transitions out of the interim PI role.

It is not unusual for the Launch PI to remain engaged with the Phase 1 unit in an ongoing capacity of approximately 1–2 days per week thereafter.

Pre-Launch Responsibilities

Support site readiness activities in partnership with Clinical Operations and Technology leadership, including protocol selection input, feasibility review, and study start‑up sequencing.

Complete credentialing, privileging, and required regulatory documentation ahead of go‑live.

Participate in site build‑out planning, including capacity, staffing, and workflow design specific to Phase 1 requirements.

Complete on‑site training at a reference NYOH/START clinic to gain familiarity with START systems, standard operating procedures, and documentation practices.

Launch-Phase Physician Investigator Responsibilities

Serve as the site’s Principal Investigator for enrolled protocols during the interim period, providing new patient consults, consent visits, safety follow‑ups, and infusion oversight as required.

Ensure timely completion of protocol‑required investigator activities, including data entry and safety reporting.

Serve as the point of clinical escalation for physician‑dependent decisions at the site until a full‑time Physician Investigator Site Leader is in place.

Coordinate with Nursing, Clinical Research Coordinators, Regulatory, and Marketing to support clinic operations and communication during the ramp‑up period.

Provide input to site leadership on study selection and portfolio fit as the unit builds its early caseload.

Support a structured handoff of patients, protocols, and site knowledge to the incoming full‑time Physician Investigator Site Leader.

Where mutually agreed, continue in an ongoing capacity within the Phase 1 unit (approximately 1–2 days per week) following the transition to full‑time leadership.

Provide mentorship to incoming and junior investigators as needed to support continuity of clinical research capability at the site.

Build a Career That Makes a Difference

At New York Oncology Hematology (NYOH), we’re more than just the Capital Region’s leader in cancer care and blood disorders—we’re a team of passionate professionals united by a shared mission: to provide compassionate, cutting‑edge care to thousands of patients each year. With six state‑of‑the‑art cancer centers across Albany, Amsterdam, Clifton Park, Hudson, and Troy—and a dedicated women’s imaging center, Akira Medical Imaging + Wellness—we bring advanced treatment close to home. Our team includes 35 board‑certified physicians and more than 300 cancer care specialists, all working together across medical oncology, radiation oncology, hematology and gynecologic oncology and surgery. At NYOH, we are committed to delivering excellent health care to help our patients continue to tell their story. If you’re looking for more than just a job—if you want a career with purpose—join us and be part of a community that’s changing lives and shaping the future of cancer care.

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