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BioSpace

Principal Scientist - Cancer Early Detection

englewood, NJ

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About this opportunity

BioSpace lists this Principal Scientist - Cancer Early Detection opportunity in englewood, New Jersey. Review the employer’s description below for duties, qualifications and application requirements.

Job description

ICR's Cancer Early Detection program is focused on building early warning systems out of arrays of blood- and urine-based biomarkers from cancer patients and healthy controls, focusing on early stage cancers. We're using machine learning to predict cancer signatures to enable early intervention when cancer is most treatable. We're hiring a Principal Scientist to lead our Cancer Early Detection Team.

With ICR, You'll Get To

Lead a cutting-edge cancer biomarkers group with the goal of detecting cancer at its earliest stages

Contribute highly practical and readily translatable pan-cancer screening/early detection, diagnostic, prevention and therapeutic ideas

Quantify and track cancer biomarkers, including CTCs, cfDNA, serum, plasma, and urine proteins, RNA, metabolites, driver-gene mutations, epigenetic modifications, etc

Collaborate with ICR's Biomarkers Team to perform molecular and cellular cancer prevention screening assays, under a personalized medicine paradigm

Please Apply If You Have

A PhD, MD or both

At least 10 years of cancer research experience, preferably in early detection and biomarkers

Current and in-depth knowledge of pan-cancer: screening, early detection, biomarkers, diagnostic prediction, genetics, prevention, and chemical and vaccine-therapeutics (practical and experimental)

Programming experience in Python

Solid grasp of biostatistics, especially probability theory

Experience with prediction modeling and machine learning, including experience using proper scoring rules

Ideally, You'll Also Have

Expert knowledge and understanding of worldwide cancer biomarker and detection assay development pipelines

Experience with cell-based assays, immunofluorescent microscopy, qPCR, flow cytometry, single-cell genomics, RNAseq, cell culture, organoid culture, Illumina NextSeq 550, DNA methylation sequencing, ddPCR, Luminex, clinical chemistry instrumentation, Kryptor, Access 2, robotic liquid handling (e.g. Tecan), Vortex, and DepArray

Experience with protein, RNA, and small metabolite cancer biomarker analysis

And You'll Need

An easygoing, friendly personality

The ability to work in the United States without sponsorship

Salary

Starting base pay range: $165,000/yr - $215,000/yr

Starting additional compensation range: $7,500/yr - $20,000/yr

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Worksite address

englewood, NJ, 07631, US

Who can apply

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