About this opportunity
KA Recruiting Inc. lists this Principal Scientist / Senior Research Scientist / Scientific Operations Principal - Histopathology & Translational Biomarkers opportunity in san francisco, California. Review the employer’s description below for duties, qualifications and application requirements.
Job description
Principal Scientist Histopathology & Translational Biomarkers
Location : Bay Area, CA
Compensation: $150,000 $200,000 annually
Employment: Full-Time, Permanent
We are seeking an experienced Principal Scientist to provide scientific leadership across histopathology, translational biomarker, digital pathology, and tissue-based research programs. This is an excellent opportunity for a Ph.D.-level scientist who enjoys solving complex scientific problems, designing and troubleshooting studies, interpreting tissue-based data, and serving as a technical resource for both internal teams and biopharma customers. This is not a traditional people-management position. The Principal Scientist will lead through scientific expertise, technical guidance, and project coordination while remaining closely involved in the science.
Responsibilities
- Provide scientific leadership for histopathology, translational biomarker, and tissue-based research programs
- Support development, optimization, and validation of IHC, IF, and other tissue-based assays
- Guide experimental design, controls, study feasibility, troubleshooting, and scientific interpretation
- Conduct literature research and translate findings into practical study recommendations
- Support digital pathology, whole-slide imaging, and quantitative image-analysis workflows
- Interpret biomarker, histopathology, and image-analysis results
- Participate in technical scoping, study planning, and scientific discussions with biopharma customers
- Provide technical guidance and mentorship to scientists and cross-functional project teams
- Support SOP development, scientific best practices, quality systems, and process improvements
Requirements
- Ph.D. in Pathology, Biomedical Sciences, Biology, Bioengineering, or a related scientific discipline
- 3+ years of experience in histopathology, translational biomarkers, or closely related tissue-based research
- Strong understanding of tissue-based assays, pathology techniques, biomarker analysis, and scientific interpretation
- Experience with IHC, IF, assay development, optimization, and/or validation
- Strong experimental design and scientific troubleshooting skills
- Experience leading scientific projects or providing technical leadership to other scientists
- Strong scientific communication and stakeholder-management skills
Preferred Experience
- Digital pathology and whole-slide imaging
- Visiopharm, HALO, QuPath, Aperio, or comparable image-analysis platforms
- Multiplex imaging, spatial biology, biomarker scoring, or cell phenotyping
- Biotechnology, pharmaceutical, CRO, or translational research environment
- CAP, CLIA, GLP, or other regulated laboratory experience
- Customer-facing scientific or technical support
If you are a Ph.D.-level scientist with a strong background in histopathology, tissue biomarkers, and translational research and are interested in taking on greater scientific leadership while remaining close to the science, we encourage you to apply.
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Worksite address
san francisco, CA, 94101, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.