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F. Hoffmann-La Roche AG

Principal Scientist: Structural Dynamics for Drug Discovery

south san francisco, CA

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About this opportunity

F. Hoffmann-La Roche AG lists this Principal Scientist: Structural Dynamics for Drug Discovery opportunity in south san francisco, California. Review the employer’s description below for duties, qualifications and application requirements.

Job description

Genentech's Department of Protein Sciences in South San Francisco seeks a Principal Scientist in Structural Biology to drive drug discovery by integrating structural data, computational modeling, and biophysical insights.

You will oversee protein construct design, expression, purification, and high‑resolution structure determination using cryoEM and/or X‑ray crystallography, while mentoring cross‑functional teams.

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Worksite address

south san francisco, CA, 94083, US

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