About this opportunity
UMass Med School lists this Research Associate IV opportunity in worcester, Massachusetts. Review the employer’s description below for duties, qualifications and application requirements.
Job description
Research Associate IV
Minimum Salary
US-MA-Worcester
Job Location
7 days ago(9/25/2026 2:27 PM)
Requisition Number
# of Openings
1
Posted Date
Day
Shift
Exempt
Union Code
Non Union Position - Non Unit Professional (W60)
Position Type
Full-Time
Min
USD $57,000.00/Yr.
Max
USD $73,000.00/Yr.
Overview
POSITION SUMMARY:
Under the direction of the Principal Investigator (PI) or designee, the Research Associate IV designs and performs a variety of complex research experiments with a high degree of independence. This position will contribute significantly to the management of the research program and will be involved in multiple aspects of the research projects and lab maintenance activities.
Responsibilities
ESSENTIAL FUNCTIONS:
Independently design and perform multiple complex laboratory experiments
Identify and utilize all software relevant to experiment and equipment used
Interpret data, form conclusions and decide on next steps with a high degree of independence
Maintain accurate records, and record results according to established lab, sponsor and University protocol
Review literature, publications and grants relevant to assigned projects
Record results according to established lab, sponsor & university protocol
Perform in-depth data analysis and/or mathematical computations
Maintain a detailed lab notebook according to lab practice
Compile and analyze data, and present in a format suitable for publication according to PI specifications
Present findings at lab/group meetings and other forums
Maintain laboratory supply levels and order as noted
Manage laboratory equipment service contracts and coordinate maintenance on laboratory equipment.
Prepare and label buffers, media, solutions, etc.
Monitor and enforce all safety regulation and infection control standards
Identify and write standard operation procedures in compliance to EHS regulation specific for the lab
Train on IACUC, EHS, Radiation safety protocols
Comply with all applicable state, federal university, and sponsor policies and agreements
Manage daily operations of the laboratory, including lab personnel, procedures and projects
Identify problems and challenges, propose resolutions, implement appropriate solutions
Develop and implement new protocols and/or modify defined protocols, as necessary, and with the approval of the PI
Prioritize and perform several tasks or procedures simultaneously with attention to detail
Perform duties and experiments with independence
Mentor and train lab personnel on proper lab conduct and techniques
Manage laboratory spending in accordance with budget guidelines provided by PI or designee
Assist with budget and/or operational aspects of grant and contract proposals
Negotiate with vendors to optimize available resources
Contribute independently to writing sections for manuscripts and grants
Direct the activities of research support staff
Perform other duties as required
Qualifications
REQUIRED QUALIFICATIONS:
Bachelor's degree in Biological or Natural Science and 5+ years of relevant research experience or a related Master's degree with 3+ years of relevant research experience.
Knowledge of Microsoft Office products
Strong ability to analyze complex visual data in a quantitative and objective manner
Ability to work in a team environment
Additional Information
The focus of the Wolfe Laboratory is the development of genome editing tools, such as base editors and prime editors, to employ as new classes of therapeutics. The successful candidate would be a part of an interdisciplinary team of laboratory scientists, clinicians, and computational biologists that are working on therapeutics for a variety of neurological and neuromuscular disorders, as well as cancer. We are looking for a candidate that would be a key player in developing and characterizing novel genome editing systems that could serve as new therapeutics - with these reagents potentially being used in clinical trials.
Experience Required:
Basic molecular biology techniques (PCR, cloning, gel electrophoresis, plasmid purification).
Mammalian Cell culture experience.
Experience Desired (not required):
Genome editing
Illumina Sequencing library preparation
Experience using mouse disease models
Major Responsibilities (in addition to the standard set) :
Participate in the development and characterization of genome editing systems tailored to correct gene mutations common in certain patient populations or kill cancer cells.
Participate in the application of these genome editing systems in relevant mouse disease models.
Organize ordering and stocking of supplies and reagents for the laboratory.
SUPERVISION RECEIVED :
Under the direction of the Principal Investigator, or designee
SUPERVISION EXERCISED:
Supervise aides, technicians, and associates
ENVIRONMENTAL WORKING CONDITIONS:
Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.