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Job description
Overview
Research Scientist II -HCMG - RADC - Full-time-20871 at Rush University Medical Center
Location: Chicago, Illinois
Business Unit: Rush Medical Center
Hospital: Rush University Medical Center
Department: Rush Alzheimers Dis Ctr-ResFac
Work Type: Full Time (Total FTE between 0.9 and 1.0)
Shift: Shift 1
Work Schedule: 8 Hr (8:00:00 AM - 4:30:00 PM)
Rush offers exceptional rewards and benefits. Pay Range: $32.00 - $52.08 per hour. Salaries are determined by factors including education, experience, skills, internal equity, and market data. Offers may vary by case.
Summary: The Staff Research Scientist will design and perform complex scientific research experiments. This person will lead research efforts on human iPSC-based disease modeling or/and CRISPR gene perturbations. The job will perform experiments, analyze data, compile results, and monitor quality control processes to ensure integrity of research. The position will utilize knowledge of molecular biology, neurobiology, cell biology, human genomics, and stem cell biology. This person will troubleshoot and evaluate data, and prepare manuscripts based on experimental results. The work requires the application of highly specialized knowledge of brain development and human genetic/epigenetic regulations. Related techniques include human iPSC cultures, neural differentiation, brain organoid cultures, high-content imaging, molecular biology, viral packaging, CRISPR gene perturbations and data analysis. Exemplifies the Rush mission, vision and values and acts in accordance with Rush policies and procedures.
Responsibilities
Mentor technicians and graduate students
Generate multi-cellular 2D and 3D culture models to incorporate different cell types
Develop cellular, molecular, and functional assays to examine AD phenotype in the dish
Conduct gene perturbation experiments to test AD candidate genes
Collect and analyze multi-module data, including imaging, FACS, qRT-PCR, targeting sequencing etc.
Coordinate other team members to successfully execute the research plan
Prepare and/or publish scientific papers and manuscripts
Contribute to grant writing
Communicate with other RADC teams on related projects
Plan and conduct statistical analysis of data
Prepare abstracts and meeting materials to present (slides, posters) within scientific group
Plan meetings (investigator meetings and other scientific/operational meetings)
Design and execute complex research procedures
Develop and perform routine and complex protocols for research programs
Assist in developing, implementing, and monitoring quality activities
Collaborate with principal investigators in determining study design and performing statistical analyses
Perform and develop routine and complex computational and database methods for implementation
Participate in meetings with principal investigator and research staff and evaluate/interpret data, develop methodologies, evaluate lab procedures
May oversee the work of laboratory personnel including training and development as well as daily work direction/delegation/prioritizing
Qualifications
Ph.D. with 3 years expertise in Neuroscience, Cell biology, Developmental biology, Stem cell biology, molecular biology, or related field or a Master’s degree with 6 years of experience
Excellent skills and experience in human iPSC cultures, neural differentiation, and brain organoid cultures
Excellent skills and experience in assay development and high-content imaging
Excellent skills and experience in molecular biology and CRISPR gene perturbations
Excellent project planning, organization, and problem-solving skills
Excellent communication and interpersonal skills
Proven ability to work independently and in collaborative team environments
Ability to work for 8 hours daily in the lab
Disclaimer: The above is intended to describe the general content of and requirements for the performance of this job. It is not to be construed as an exhaustive statement of duties, responsibilities, or requirements.
Other Information
Rush is an equal opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and other legally protected characteristics.
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Worksite address
chicago, IL, 60290, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.