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Job description
About The Role
Responsible for lead generation biology platforms that support Neurocrine’s early research portfolio. Oversees broad assay development, routine cellular and biochemical pharmacology assays for SAR, SPR and other biophysical/binding approaches, and fit-for-purpose screening workflows across therapeutic areas, target classes, and drug modalities.
Leads a laboratory organization to deliver robust, high-quality pharmacology data through scalable, reproducible, well-characterized experimental workflows, partnering with therapeutic areas, protein engineering, chemistry, and other cross-functional R&D teams.
Your Contributions (include, but are not limited to)
Lead discovery biology platform capabilities: assay development; cellular/biochemical SAR assays; SPR/biophysical approaches; fit-for-purpose screening workflows
Oversee development, optimization, validation, and implementation of robust assay systems for reproducible pharmacology data
Proven record in pathophysiology underlying immunology, neurodegenerative, neuropsychiatric, and/or endocrine disorders
Partner cross-functionally (therapeutic areas, protein engineering, chemistry, translational science, DMPK, automation, informatics)
Lead/manage laboratory execution, data quality, platform performance, and continuous improvement
Evaluate/implement new technologies, assay formats, instrumentation, and workflow improvements
Mentor and train scientists/technical staff
Provide assay feasibility guidance, screening cascade design input, and interpretation
Establish/manage external collaborations (CROs, technology providers, academic/industry partners)
Represent platform capabilities in forums/meetings; stay current via conferences/publications
Requirements
BS in biological sciences (behavioral neuroscience/pharmacology/biopsychology) + 12+ years pharma/biotech OR MS + 10+ years OR PharmD/PhD + 8+ years
Deep knowledge of discovery biology, assay development, SAR-supporting assay cascades, biophysical methods, and early drug discovery platforms
Experience developing/optimizing/scaling assays across cellular, biochemical, and biophysical modalities (including SPR)
Strong leadership, communication, problem-solving, analytical thinking, and collaboration
Preferred: experience evaluating/implementing new technologies, automation, or data-analysis workflows
Benefits (as stated)
Annual bonus target 35% of earned base salary; equity long-term incentive eligibility
Retirement savings plan (company match); paid vacation/holidays/personal days; paid caregiver/parental and medical leave; medical/prescription/dental/vision coverage
Compensation (as stated)
Annual base salary: $188,700.00–$257,000.00
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Worksite address
san diego, CA, 92189, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.