About this opportunity
Regeneron Pharmaceuticals, Inc. lists this Scientist, Cardiac Vascular - In Vivo opportunity in village of tarrytown, New York. Review the employer’s description below for duties, qualifications and application requirements.
Job description
When & where:
Location: Tarrytown, NY
Work model/flexibility: Onsite
Discover your role:
Perform surgical models of cardiac and vascular disease in mice and rats, including transverse aortic constriction (TAC), myocardial infarction (MI), and renal/kidney models (RKM)
Administer test articles via multiple routes (IV, SC, IM) or osmotic minipump implantation with precision and consistency across longitudinal study timelines
Implant and manage telemetry devices for continuous blood pressure and ECG monitoring in conscious, freely moving rodents
Conduct invasive hemodynamic assessments using PV-loop methodology to quantify cardiac function
Perform ex-vivo tissue collection and processing, including cardiac dissociation via Langendorff perfusion
Manage end-to-end in-vivo study logistics, including animal health monitoring, surgical scheduling, and post-operative care
Analyze and interpret physiological, hemodynamic, and functional data using PRISM, PONEMAH, and other relevant analysis software
Generate high-quality figures, reports, and data summaries for internal presentations, regulatory packages, and peer-reviewed publications
Maintain rigorous records of surgical procedures, animal welfare documentation, and study protocols in compliance with institutional and regulatory standards
Collaborate closely with study directors, therapeutic area scientists, and cross-functional teams to align surgical and analytical approaches with program goals
Proactively flag capacity constraints, scheduling conflicts, or technical challenges to stakeholders
This role requires:
BS with 10+ years, MS with 6+ years with relevant experience in a related field (e.g., Physiology, Biomedical Sciences, Veterinary Science, or similar)
Demonstrated hands‑on expertise in rodent cardiac and vascular surgical models (TAC, MI, RKM)
Proficiency in rodent dosing techniques (IV, SC, IM) and telemetry implantation for blood pressure and ECG monitoring
Experience with invasive hemodynamic measurement techniques, including PV-loop analysis
Hands‑on experience with Langendorff perfusion and cardiac tissue dissociation
Proficiency with data analysis software such as PRISM and PONEMAH
Strong understanding of rodent anatomy, physiology, and survival surgery best practices
Excellent organizational skills, with the ability to manage multiple longitudinal studies and competing priorities simultaneously
Strong attention to detail and commitment to scientific rigor and animal welfare standards
Excellent oral and written communication skills
Preferred: experience with additional cardiovascular functional assessment techniques or prior work in a GLP/regulated research environment
Does this sound like you?
We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.
Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits,
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Who can apply
Review the original listing for work authorization, qualifications and employer requirements.