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Job description
Scientist III, Biotherapeutics Discovery - Lead Discovery (In Vitro Display)
Description
Boehringer Ingelheim is currently seeking a talented and innovative scientist to join the Biotherapeutics Discovery department located at our Ridgefield, CT facility. The position offers an exciting opportunity to engage in the discovery and molecular engineering of Biotherapeutics for unmet medical needs. You will be an integral member of the Lead Discovery group and will perform phage and yeast display selection (panning and screening), design and construct antibody libraries, and analyze DNA sequence and experiment data. This role will also contribute to the continued advancement of in vitro discovery workflows through close interaction with automation, sequencing, and cross-functional scientific partners.
As part of Boehringer Ingelheim, the successful candidate will contribute to the discovery, development, and delivery of products to patients and customers. The organization’s global presence provides opportunities for international collaboration, increasing visibility and enabling meaningful contributions to the company's success. Boehringer Ingelheim recognizes that its strength and competitive advantage lie in its people and supports employees through a healthy working environment, meaningful work, mobility, networking, and work-life balance. Competitive compensation and benefit programs reflect the company's high regard for its workforce.
Duties & Responsibilities
Perform phage and yeast display selections for antibody discovery
Design, construct, and implement in vitro antibody libraries for lead identification and lead optimization, e.g., affinity maturation
Screen biologic drug candidates using ELISA and related techniques
Develop and execute high-throughput screening using automation technologies
Independently write protocols and technical reports in accordance with company policies
Independently present/defend scientific findings in project team or Department meetings
Actively participate in cross-functional teams/initiatives
Design and execute experiments with minimal supervision
Independently analyze and interpret experimental results
Collaborate with cross-functional partners to support data-driven hit prioritization, workflow optimization, and efficient progression of discovery campaigns
Contribute to the continuous improvement of discovery workflows, including adoption of new technologies for screening, sequencing, and data analysis
Requirements
Master’s Degree from an accredited institution with three-plus (3+) years of experience in related scientific discipline, OR Bachelor’s Degree from an accredited institution with seven-plus (7+) years of experience in related scientific discipline or equivalent experience in related field
Experience in phage, yeast, or other display technology
Demonstrated mastery of molecular biology methods including primer design, PCR, gel electrophoresis, cloning, and sequence analysis
Experience in characterization assays such as ELISA and related techniques
Concise and accurate reporting of technical data and information
Ability to work in team-oriented environment
Excellent organizational skills
Excellent written and verbal communication skills
Desired experience, but not required:
Previous experience in lab automation
Experience with flow cytometry
Solid understanding of antibody discovery principles and familiarity with relevant technologies
Demonstrated experience and knowledge of DNA sequence analysis tools such as Geneious or similar
Familiarity with NGS-enabled antibody discovery workflows and interpretation of sequence-derived datasets
Exposure to AI/ML-enabled workflows that support antibody library design, hit prioritization, sequence analysis, or developability assessment
Experience working with bioinformatics, automation, or data-science partners in a multidisciplinary discovery environment
Exposure to digital laboratory tools or data systems (e.g., ELN/LIMS/Genedata Biologics/Benchling or similar) that support reproducible and scalable discovery workflows
Eligibility Requirements
Must be legally authorized to work in the United States without restriction.
Must be willing to take a drug test and post-offer physical (if required)
Must be 18 years of age or older
Compensation Data
This position offers a base salary typically between $87,000 and $130,600. The position may be eligible for a role specific variable or performance-based bonus and or other compensation elements. For an overview of our benefits please click here.
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Worksite address
ridgefield, CT, 06877, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.