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Initial Therapeutics, Inc.

Scientist – Protein Engineering – Organic Chemist: ADC Research & Development

thousand oaks, CA

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Job description

Scientist Protein Engineering Organic Chemist: ADC Research & Development

What you will do

Lets do this. Lets change the world. In this vital role you will work at the interface of synthetic chemistry, biochemistry, and chemical biology to apply their synthetic skills in developing ADC therapeutics and cutting‑edge novel modalities.

Key Responsibilities

Design, synthesize, purify, and characterize linker‑payloads for antibody‑drug conjugates (ADCs).

Design and generate ADCs, including conjugation, purification, and characterization to support therapeutic discovery.

Analyze and interpret data, and communicate results through clear documentation, reports, and project updates.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Scientist we seek is a researcher with these qualifications.

Basic Qualifications

Doctorate degree

Master’s degree and 2 years of organic chemistry and laboratory experience

Bachelor’s degree and 4 years of organic chemistry and laboratory experience

Preferred Qualifications

Strong proficiency in organic synthesis and chemical methodology development

Knowledge of, or experience with, protein conjugation and protein chemistry techniques

A robust understanding of structural determination using NMR and MS, with proficiency in chromatographic techniques (e.g., HPLC, RP‑HPLC, ion exchange, and size‑exclusion chromatography)

Demonstration of good lab practices, with particular attention to safety

Strong written and verbal communication skills

Ability to work comfortably within a team of scientists and engineers with diverse technical and cultural backgrounds

Benefits

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save toward retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan

Stock‑based long‑term incentives

Award‑winning time‑off plans

Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Equal Opportunity Employer

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, or disability status.

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Worksite address

thousand oaks, CA, 91362, US

Who can apply

Review the original listing for work authorization, qualifications and employer requirements.

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