About this opportunity
QLD Biotherapeutics Inc lists this Scientist/Senior Scientist, iPSC Differentiation opportunity in boston, Massachusetts. Review the employer’s description below for duties, qualifications and application requirements.
Job description
At QLD Biotherapeutics, we develop cell and gene therapies using innovative technologies to treat devastating diseases. We are seeking a highly motivated and talentedScientist/Senior Scientistto join our Cellular Therapy Group to advance our efforts in induced-pluripotent stem cell (iPSC)-derived cell therapies. The successful candidate will focus on developing novel iPSC-derived cell differentiation platform to support best-in-class cell therapy development.
This position provides an excellent learning and growth opportunity, to work closely with an experienced drug discovery and development team and contribute to early stages of research and development activities in a fast-paced and highly collaborative environment.
Primary Responsibilities
Design and optimize novel, scalable and robust iPSC differentiation platforms to produce beta-islet cells and neuronal cells with high efficiency and purity, for treatment of diabetes and neurological diseases.
Develop and validate characterization assays to determine the various differentiation stages using cellular and molecular methods.
Reprogram somatic and blood cells and bank corresponding iPSC clones.
Analyze and interpret the data and be responsible for timely and effective communication of data and results to the project teams.
Manage study progress, ensure data accuracy and integrity.
Prepare key preclinical documents, and patent application, including, but not limited to study protocols, and study reports to support IND filling
Identify potential project hurdles, suggest solutions, and contribute to contingency plans.
Works collaboratively within internal cross-function teams and external CRO/academic institutes
Adhere to the appropriate SOP and GxP guidelines, and embrace a collaborative culture
Qualification:
PhD in developmental biology, immunology, cell biology, or related field with 3+ years of post-doctoral, academic faculty, or industrial experience
Expertise at iPSC or stem cell differentiation, culture, banking and characterization
Experience in cellular and gene engineering using CRISPR, lentivirus, transposon and LNP is preferred
Experience with multiplex flow cytometry and whole genome sequencingis preferred
Track record of independent research and creativity, as demonstrated by first author publications
Excellent organizational and time management skills and must be a self-starter with the ability to thrive in a multi-disciplinary, collaborative, fast-paced, and team-oriented environment.
Excellent verbal and written communication skills.
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Worksite address
boston, MA, 02298, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.