About this opportunity
ImmuneBridge, Inc. lists this Scientist / Senior Scientist, Process Development opportunity in san francisco, California. Review the employer’s description below for duties, qualifications and application requirements.
Job description
About ImmuneBridge
ImmuneBridge is building the next generation of cell therapies. Our mission is a world where high-quality cell therapies can be rapidly designed and easily manufactured at commercial scale and ultralow cost.
About the Role
Title: Scientist or Senior Scientist, Process Development
Reports to: Chief Technology Officer
Location: in-person, 5 days per week, San Francisco, CA
Compensation: $110,000-$160,000 plus equity
Benefits: health, dental, vision insurance; 401k with employer match; unlimited PTO
Job Description
We are hiring a hands-on process development scientist to own our bioreactor work. Reporting to the CTO, you will run and optimize rocking-motion bioreactor processes for stem cell expansion and immune cell differentiation, and help carry our platform from the bench toward clinical-scale manufacturing. The right candidate will perform:
Bioreactor operation: Set up, run, and monitor rocking-motion (wave-type) bioreactor campaigns, including perfusion, and own key parameters such as pH, DO, seeding density, and feed/perfusion rates.
Process development: Design and execute experiments (DoE where it fits) to improve expansion, yield, and run-to-run consistency; troubleshoot failed runs to root cause.
Scale-up: Translate plate- and flask-scale processes to multi-liter bioreactor scale and build scale-down models.
Characterization: Use cell counting and flow cytometry to track viability, identity, and phenotype; analyze data and recommend next steps.
Documentation and tech transfer: Write protocols, run records, and development reports; present data to leadership; support future tech transfer to CDMO partners.
Required qualifications
BS in bioengineering, chemical or biochemical engineering, cell biology, immunology, or a related field. Advanced degrees welcome; level is set by depth of hands-on experience.
Hands-on bioreactor experience with mammalian or primary cells, ideally rocking-motion systems (e.g., Cytiva WAVE/Xuri or similar), including developing or optimizing protocols.
Strong aseptic technique, cell culture skills and media/solution preparation; sound experimental design; data analysis skills.
Good verbal and written communication skills.
Comfort with ambiguity and a startup pace.
Ability to work on-site in San Francisco 5 days/week, mostly in the lab.
Attention to detail and excellent documentation skills.
Preferred qualifications
Cell therapy process development experience (HSC, NK, T cell, or other immune cells).
Perfusion or fed-batch process experience; flow cytometry.
Exposure to GMP, tech transfer, or CDMOs.
Prior startup experience.
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Worksite address
san francisco, CA, 94199, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.