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Job description
Role Description
As a Senior Associate Scientist in the Biopharmaceutical Pilot Registration Lab, you will play a vital role in the development, scale-up, and technology transfer of CHO-expressed monoclonal antibodies for veterinary use. You will operate in a GMP-regulated environment, collaborating with multidisciplinary teams to ensure a successful transition from development to pilot to commercial manufacturing. This role requires hands-on technical expertise in upstream and/or downstream processing, as well as strong organizational and communication skills. The position is based in Lincoln, Nebraska with frequent interactions with colleagues and external partners located around the globe.
Position Responsibilities
Advanced experience in setting up, programming, operating and troubleshooting large-scale equipment for expression (mammalian cell culture) and/or purification of recombinant therapeutic proteins
Represent the lab as a key technical leader in cross-functional project teams, collaborating with process development and manufacturing teams, driving process optimization and scale-up, ensuring seamless, high-quality technology transfer
Demonstrate advanced expertise in authoring and reviewing process documentation, SOPs, protocols, technology transfer documents and regulatory filings ensuring the highest standards of scientific rigor and quality
Hands-on execution and support of upstream cell culture (shake flask to 2000-L production scale) and/or downstream purification (centrifugation, chromatography, filtration) to produce GMP batches of drug substance.
Drive continuous improvement by optimizing existing workflows and procedures
Ensure accurate and compliant documentation in accordance with current GMP standards
Perform preventative maintenance on portable and stationary equipment
Maintain, clean, and perform steam-in-place procedures for equipment
Education and Experience
Bachelor's degree (minimum) in biological sciences, chemical engineering, or related field. Advanced degree would be advantageous.
Significant practical experience and theoretical knowledge of upstream cell culture and/or downstream processing (centrifugation, filtration, chromatography)
Proven track record in GMP-regulated environments, including process scale-up and tech transfer to commercial facilities.
Technical Skills Requirements
Strong scientific and engineering background in the principles for process scale-up and robustness
Experience with instrumentation, control systems, and advanced troubleshooting for pilot-scale GMP operations, including practical experience with automated control and data capture systems such as SCADA, Delta V, and Unicorn
Knowledge of equipment specification, qualification, operation, and maintenance in a regulated environment
Experience with large-scale bioreactor and/or purification equipment
Working knowledge of GMP systems (change control, SAP, LIMS) is desirable
Willingness to work flexible hours, including after-hours monitoring as needed
Ability to perform physically demanding tasks typical of a pilot-scale lab environment
Excellent aseptic technique
Experience with cGMPs, inspection, and compliance
Demonstrated ability to work independently on multiple concurrent programs
Familiarity with regulatory frameworks for veterinary biopharmaceuticals is desirable
Strong organizational and people skills
Excellent written and verbal communication skills
Proven ability to work effectively as part of a collaborative team
About Zoetis
At Zoetis, our purpose is to nurture the world and humankind by advancing care for animals. As a Fortune 500 company and the world leader in animal health, we discover, develop, manufacture and commercialize vaccines, medicines, diagnostics and other technologies for companion animals and livestock. We know our people drive our success. Our award-winning culture, built around our Core Beliefs, focuses on our colleagues' careers, connection and support. We offer competitive healthcare and retirement savings benefits, along with an array of benefits, policies and programs to support employee well-being in every sense, from health and financial wellness to family and lifestyle resources.
Notice
Zoetis Recruiters will contact candidates via email from an address ending in @zoetis.com and may also initially connect with candidates through LinkedIn , including LinkedIn InMail. Zoetis does not use Gmail, Outlook, Yahoo, or other web-based/generic email domains to communicate about job opportunities, interviews, or offers of employment. If you receive a recruitment-related email message claiming to be from Zoetis that does not come from @zoetis.com, please treat it as suspicious. For your security, do not reply, click links, open attachments, share personal or financial information, or send money in response to unexpected or questionable recruitment communications.
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Worksite address
lincoln, NE, 68511, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.