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Job description
Janux Therapeutics is seeking a Senior Director, Clinical Supply Chain who will lead and execute Janux’s clinical supply strategy across Phase 1–3 programs, with a focus on enabling progression into late-stage development. This is a hands‑on leadership role responsible for ensuring uninterrupted global supply of investigational medicinal product (IMP) while building scalable processes to support growing clinical program complexity.
This role partners closely with Clinical Operations, CMC, Quality, and Regulatory to align supply planning, manufacturing, and trial execution. The ideal candidate brings deep experience in biologics and global clinical trial supply, including hands‑on support of late‑stage clinical programs in a fast‑paced biopharma environment.
Essential Functions And Responsibilities
Lead and develop clinical supply strategies across Phase 1–3 programs
Ensure uninterrupted supply of IMP across global, multi‑region clinical trials
Lead the team in end‑to‑end clinical supply operations, including packaging, labeling, distribution, returns, reconciliation and destruction.
Provide strategy and support in global logistics, including import/export activities and depot strategy, ensuring compliance with country‑specific labeling and regulatory requirements
Provide strategic leadership, cross‑functional alignment, and operational oversight to ensure the successful execution of key activities across Clinical Operations, Quality, Regulatory, and CMC functions.
Contribute to and review clinical trial documentation, including clinical protocols, pharmacy manuals, batch records, drug labels, and shipping documentation. Provide oversight of IRT strategy, setup, and execution
Partner closely with CMC to align manufacturing schedules with clinical supply needs and scale‑up activities. Oversee comparator sourcing and supply strategies as needed
Select, manage, and oversee external vendors (CDMOs, depots, packaging and logistics providers), including RFPs, SOWs, and performance management
Partner with QA on vendor qualification, audits, compliance activities, and the development and maintenance of supply chain‑related SOPs and processes.
Ensure compliance with GcPs, and global regulatory requirements
Support inspection readiness and regulatory submissions related to clinical supply
Develop and manage clinical supply budgets, forecasts, and spend tracking
Provide regular updates to leadership on supply status, risks, and planning assumptions
Lead, mentor, and develop a small clinical supply team and build scalable processes to support company growth
Education, Experience, Knowledge, Skills And Abilities
Bachelor’s degree in life sciences, supply chain, or related field
12+ years of experience in biotech/pharma supply chain with 4+ years of people management experience within a clinical supply chain organization.
Strong experience supporting Phase 2 and Phase 3 clinical trials
Proven experience supporting global clinical trials (including EU, APAC, Canada), including multi‑region labeling and distribution requirements
Biologics experience required; oncology therapeutic area background strongly preferred
Demonstrated ability to operate in a hands‑on role within a small to mid‑size biotech environment
Strong expertise in clinical supply planning, forecasting, and inventory management
Experience managing external vendors, including CDMOs, depots, and logistics providers
Strong working knowledge of IRT systems and clinical supply infrastructure
Solid understanding of GcP guidelines, 21 CFR and Annex 13 requirements
Oncology experience strongly preferred
Experience supporting transition from early‑stage to late‑stage clinical development
Experience building or scaling clinical supply chain functions in an emerging biotech environment
Strong leadership and people management skills, with the ability to mentor and develop team members
Excellent cross‑functional communication and stakeholder management skills
Ability to operate effectively in a fast‑paced, evolving environment and navigate ambiguity
Strong problem‑solving skills with a focus on practical execution
$257,000 - $275,000 a year
In addition to a competitive base salary ranging from $257,000 to $275,000, we offer stock options, restricted stock units, a stock purchase plan (ESPP) and a target bonus. Janux also provides a comprehensive benefits package for our employees and their families, which includes medical, dental, vision, and supplemental disability insurance. Relocation assistance may also be available.
Please note that the base salary range is a guideline, and individual total compensation will vary based on factors such as qualifications, skill level, competencies, internal equity, and work location.
Job Type: Full-time
Benefits
Annual bonus program
Incentive stock option plan
401k plan with flat non‑elective employer contribution
Comprehensive medical insurance with 90‑100% employer‑paid premiums
Dental and vision insurance
HSA, FSA, and supplemental insurance plans (life, disability, accident, critical illness, hospital indemnity)
Unlimited PTO
Generous holiday schedule; includes summer and winter company shutdown
Relocation assistance
Schedule
Monday to Friday
Work Authorization
United States (Required)
Additional Compensation
Annual targeted bonus %
Work Location:
On site (San Diego, CA)
Janux Therapeutics, Inc. is an equal opportunity employer that is committed to providing a work environment free of harassment and discrimination based upon a protected category, as well as an environment free from retaliation for protected activity.
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Worksite address
california, MO, 65018, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.