Senior Director of Trade and Channel Management

Job description

Senior Director of Trade and Channel Management

Olema Oncology is a clinical-stage biopharmaceutical company committed to transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It’s an exciting time to be part of Team Olema , with our transfor mation into a fully integrated oncology company well underway , t op-line data from our lead program expected later this year , and our first potential commercial launch on the horizon.

Our leadproduct candidate,palazestrant, isa novel, orallyavailablecomplete estrogen receptor antagonist (CERAN)and selective estrogen receptor degrader (SERD)currently intwopivotalPhase 3clinicaltrials.We expect top-line data from OPERA-01,ourongoingPhase 3 trial ofpalazestrantas a monotherapy in patients withsecond- or third-lineER+/HER2-metastatic breast cancer (MBC), in the fallwhich, if successful, could lead to our first potentialapproval andcommercial launchin 2027. OPERA-02,ourPhase 3 trial ofpalazestrantin combination withribociblibin patients with frontlineER+/HER2- MBC, isenrolling patients.Togetherwith itsmechanism of action, pharmacokinetic properties,andthe potential todemonstrateactivity in bothESR1wild-type and mutant tumors,palazestranthas the potential totransform the metastatic breast cancer treatment paradigm andaccessa$15 billionglobal market opportunity.

Our follow-on product candidate, OP-3136, is a potent KAT6 inhibitor withthepotential to generate further value and meaningfullyimpactthemetastatic breastcancertreatment landscape – particularly in combination withpalazestrant.We recently reportedencouragingPhase 1monotherapydata from this programacross multiple solid tumor types andareadvancingpatientenrollment in theongoingcombinationarmsin MBC.

Aspiring to transform the metastatic treatment paradigmis an ambitious endeavor that requires aresolute approach todeveloping better therapies and apassionateteamdedicated tohelping the patients we serve feelbetter,longer.Wepossessadeepcommitment toour shared purpose,thesustained pursuit of excellence, cultivatingthecouragerequiredto advance our programs, drive to succeed, and a collective capacity for adaptability through learning, growth, and evolution. Team Olema is made up of nimble self-starters who bring consistency in their quest for the extraordinary every single day.

Ifyou’rereadyto bepartof atenacious,courageous,agile, andgrowingteam,join us in makinga profound impact,together– for our patients, for your career, and for what’s beyond .

About the Role>>>SeniorDirector of Trade and Channel Management

As the Senior Director of Trade and Channel Management reporting to the Vice President of Market Access, you will be responsible for the strategic design, implementation, and optimization of a high-performing distribution network that ensures patient access while maximizing commercial value.

As a key leader within the U.S. Market Access function, you will oversee the total distribution ecosystem, including Specialty Pharmacy, Distribution and 3PL, while driving the long-term roadmap for trade operations and ensuring the organization is positioned to scale for future therapeutic innovations.

This role is based out of either our Boston or San Francisco office and will require approximately 20%travel.

Your work will primarily encompass:

Strategic Trade & Distribution Architecture

Define and lead the long-term U.S. distribution strategy and the design of a distribution network to support the launch of our future oncology product(s), including a selection process to select key externals partners (ie. SP, SD, 3PL, etc)

Provide active account management for specialty pharmacies, wholesalers/distributors, 3PL and other key trade partners to support product availability, service performance, and operational excellence

Establish, monitor, and manage key performance indicators, service-level expectations, inventory metrics, dispense data, and reporting requirements for channel partners; hold partners accountable while maintaining strong relationships

Ensure patient accessibility to product through trade partners and specialty pharmacies while supporting compliant processes and appropriate operational controls

Lead cross-functional teams with Patient Services, Commercial Operations/Analytics, Finance, IT, Field Sales, Legal/Compliance, Contracting, and Supply Chain to implement channel strategies, improve workflows, strengthen data quality, and track progress against established goals

Serve as the lead negotiator for enterprise-level contracts with major Wholesalers, Specialty Distributors, and Specialty Pharmacies to optimize channel fee structures and service requirements

Develop and implement an optimizeddistribution and contracting strategywhichcananticipateindustry shifts and proactively adapt thedistribution model to maintain a competitive advantage

Overseelaunchreadinessfor activitieswithin theTrade andDistributionaswe prepareforthe launchour lead clinical asset as well asall pipeline assets and lifecycle management initiatives

Lead transformation initiatives in Trade & Distribution including process redesign, systems modernization, vendor optimization, and automation to improve efficiency, scalability, and data accuracy

Forecasting, Financial Governance & GTN

Own the trade-related components of the Gross-to-Net (GTN) strategy, providing executive leadership with visibility into channel costs, inventory fluctuations, and potential financial risks

Drive the integration of channel data into enterprise forecasting models to ensure high-accuracy demand planning and inventory management

Implement advanced analytics tomonitorchannel health, utilizing data-driven insights to mitigate product diversion, stockpiling, or supply disruptions

Establish and evolve KPIs and performance frameworks to assess and guide trade performance and strategic effectiveness

Collaborate with finance and other internal stakeholders to set up and manage systems/processes to track order to cash as well as fulfill government reporting obligations

Leadership and Organizational Influence

Collaborate with other members of theU.S. Market Access, Finance, and Commercial Operation, Supply Chain,Financeand othercross-functionalteammembersto align trade strategy with broader corporate financial and patient access goals

Manage external partners and vendors to ensure effective and efficient management of day-to-day U.S. Trade and Distribution operations

Demonstrate high levels of emotional intelligence, situational awareness, and ability to build and influence a positive team culture

Actively participate and contribute to the Market Access leadership team and other formal or informal cross-functional teams as needed

Ideal Candidate Profile >>

A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies forimproving lives. Allemployeeswithin our company play aunique andcrucial rolein our success, both inaccomplishingour mission and buildinga positivecompany culture. As such, we are looking forsomeone withthe right combination of knowledge, experience, and attributes for this role.

Education and Required Skills

Education: Bachelor’s degree required; MBA or advanced degree in supply chain management or healthcare administration preferred

Experience: 15+ years of progressive leadership experience in pharmaceutical trade and distribution, with a proven track record of working with partners in specialty pharmacy, distribution and 3PL

Therapeutic Knowledge: Experience with oral oncology products is required and knowledge of the oncology provider space, specifically large and complex customers (GPOs, Institutions, IDNs, etc…) will be essential

Technical Expertise: Knowledge and experience with key Trade and Distribution technologies, well as with relevant federal and state legislation

Strategic Negotiation: Demonstrated success in leading high-stakes negotiations with national wholesalers and large-scale oncology providers

Launch Leadership: Extensive experience leading trade strategy for successful U.S. product launches, particularly in the oncology drug space, with relevant and recent experience launching oral oncology products

Cross-Functional Collaboration Skills: Demonstrated ability to work cross-functionally and to influence stakeholders with the aim of creating and maintaining an optimized distribution system/processes which optimizes GTN and prioritizes customer service

Performance Management: Works with vendors and external partners to drive performance while maintaining relationships

Analytical Skills: Set and maintain clear performance objectives and KPIs which ensure alignment with broader US commercial and global market access priorities

The base pay range for this position is expected to be $270,000 - $300,000 annually, however the base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits.

We provide equal opportunity to all employees and applicants for employment and believe that great ideas and discoveries come from a mix of expertise, background, and experience. Olema is building a culture where the value of difference is celebrated.

We offer a competitive compensation and benefits package , seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants.

Please note: Olema doesn’t accept agency resumes and is not responsible for any fees related to unsolicited resumes. Thank you.

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Worksite address

boston, MA, 02298, US

Who can apply

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