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Job description
Senior Research Associate – Scientist I, Discovery Biology
The Opportunity
Plan, execute, and analyze in vitro cell-based assays to support small molecule and degrader-antibody conjugate discovery efforts in cancer oncology, including mechanistic studies and new target identification
Perform routine and specialized cell culture (cancer cell lines and/or primary cells) to support lead progression and follow-up studies
Independently troubleshoot experimental issues and proactively introduce new techniques and efficiencies to accelerate drug discovery
Analyze and interpret experimental data to quantify drug potency and activity, and communicate results clearly to project teams
Upload and maintain experimental data in electronic lab notebooks and enterprise databases with a high level of accuracy and timeliness
Collaborate closely with scientists across disciplines, contributing to experimental design, meeting presentations, and project strategy
What You’ll Bring
Bachelor’s degree with 8+ years of relevant industry experience, Master’s degree with 4+ years, or Ph.D. with 1-2 years of industry experience in Cell Biology, Cancer Biology, Molecular Biology, or a related field (final level based on education, experience, and demonstrated independence)
Strong background in cancer cell biology
Extensive hands‑on experience with cell culture (cancer cell lines and/or primary cells) and good aseptic technique
Hands‑on experience and proficiency with low‑to‑medium‑throughput cell‑based assay platforms such as HTRF, AlphaLISA/ELISA, CellTiter‑Glo, RT‑qPCR, flow cytometry, and Western blotting/JESS, and other functional assay development
Ability to conceive, design, and execute hypothesis‑testing experiments that directly contribute to project success with minimal supervision
Strong organizational skills, attention to detail, data integrity, and commitment to reproducible research
Clear written and verbal communication skills and demonstrated effectiveness working with cross‑functional teams
Ability to balance multiple studies and deliver high‑quality results against project timelines
Preferred
Experience with gene editing such as CRISPR and RNA interference
Experience with targeted protein degradation, including PROTACs, degrader-antibody‑conjugates, and molecular glue degraders
Prior industry drug discovery experience
Location: Onsite – Brisbane, CA
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Worksite address
brisbane, CA, 94005, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.