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Job description
Design and implement in vitro pharmacology readouts using cellular biochemical, functional, and image-based endpoints
Use ELISA/MSD, quantitative WB, high-content imaging, and bioluminescence-based assay formats
Provide technical and scientific leadership for immuno-histochemical endpoints in CNS and other tissues
Contribute to a collaborative high-content imaging working group focused on best practices and robust assay-design solutions
Generate data promptly to support program decision-making and communicate results to teams and senior leadership
Set and maintain high standards for data analysis and quality control
Lead internal discussions on innovative approaches to data interrogation
Interface with automated biology to identify automation-amendable assay strategies and transfer automation-ready assays
Collaborate across multiple Neuroscience project teams in a matrixed environment
Develop and train other scientists across the research organization
Requirements
Demonstrated ability to balance speed with rigor in a fast-paced, dynamic drug discovery environment
Aptitude for systematic troubleshooting of biological assay systems
Capacity and enthusiasm to grow into a leader of a small team of scientists
Must be legally authorized to work in the US without employer sponsorship now or at any time in the future
Ability, with or without accommodation, to lift/carry 15/30 pounds unassisted/assisted
Comfortable working in a controlled environment with and around biological, infectious, and hazardous materials
Ability to gown/degown PPE
Ability to use a computer and communicate via phone, video, and electronic messaging
Ability to engage in problem solving, analysis, and dialogue
Ability to collaborate with others and maintain general availability during standard business hours
B.S. / M.S. with 12+ years, or Ph.D. with 2–5 years, of imaging, cellular and molecular biology, pharmacology, biochemistry, assay development, and biomolecular screening experience
Neuroscience background with pharma/biotech experience preferred
High-content imaging and histo-chemistry experience strongly preferred
Core Competencies
Demonstrates expertise in in vitro pharmacology, assay development, and high-content imaging, with a strong emphasis on data analysis and quality control. Proven ability to lead teams and collaborate effectively in a dynamic drug discovery environment.
Highest-signal resume keywords
In Vitro Pharmacology
High-Content Imaging
Assay Development
Data Analysis
Neuroscience Background
ATS Optimization Keywords
Hard Skills
ELISA
Quantitative WB
Bioluminescence-Based Assays
Immuno-Histochemistry
Biochemical Assays
Cellular Biology
Molecular Biology
Pharmacology
Biochemistry
Biomolecular Screening
Soft Skills
Problem Solving
Collaboration
Leadership
Communication
Troubleshooting
Industry Keywords
Pharma
Biotech
Drug Discovery
CNS
Controlled Environment
Tools & Technologies
Automated Biology
PPE Gowning
Data Interrogation Tools
High-Content Imaging Systems
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Worksite address
new haven, CT, 06540, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.