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Job description
ModeX Therapeutics is seeking a highly skilled and motivated Senior Scientist with strong hands‑on experience in Immuno‑oncology/Immunology to support the development and progression of novel immune therapies. The successful candidate will design, execute, and interpret cell‑based studies using primary immune cells and relevant assay systems to evaluate biologic drug candidates, characterize their mechanism of action, and address biological questions. This is an exciting opportunity for a collaborative scientist who enjoys working at the bench, brings strong biological insight, and wants to contribute to the development of next‑generation therapeutics in a fast‑paced, rapidly growing biotech company with a bold vision.
Key Responsibilities
Play a key role in the development of new biologic drugs for Immunotherapy and Immunology
Independently design, execute, analyze, and interpret in vitro/ex vivo studies to characterize drug candidates and their mechanisms of action
Develop and perform complex immune cell‑based functional assays using primary immune cells (human and mouse), tumor cell lines, reporter systems, and co‑culture models
Design, optimize and troubleshoot multicolor flow cytometry panels, including compensation/unmixing, antibody titration and gating strategies
Analyze experimental data, generate clear conclusions, and provide data‑driven recommendations to advance research programs
Collaborate cross‑functionally with discovery, translational and project teams to ensure data‑driven decision‑making and timely progression of programs.
Contribute to scientific reports, presentations, and project updates, and effectively communicate findings to cross‑functional teams
Maintain accurate documentation of experimental activities and ensure compliance with applicable laboratory standards and data integrity practices.
Qualifications
Ph.D. or M.S. Degree in Immunology, Cancer Biology, Cell biology, Immuno‑oncology, or a related scientific field, with 10+ years of relevant research experience, including at least 4+ years in a biotech or pharmaceutical R&D environment
Strong, hands‑on expertise in Immunotherapy and Immunology, with the ability to independently evaluate and apply new concepts and immunoassays
Demonstrated experience designing, executing, and interpreting functional assays using primary immune cells, including multi‑parameter flow cytometry, cytokine profiling (ELISA, MSD, Luminex, or equivalent), immune activation, proliferation, and cytotoxicity assays.
Hands‑on experience with flow cytometry panel design, optimization, and data analysis; spectral flow cytometry experience is desirable
Proven ability to work independently, prioritize effectively, and drive projects forward in a fast‑paced biotech environment
Excellent written and oral communication skills, including the ability to present complex data clearly to scientific and cross‑functional audiences
Strong troubleshooting, organization, data analysis, and problem‑solving skills
Highly collaborative mindset with the ability to contribute ideas, work across teams, and mentor junior team members as needed
ModeX Therapeutics is an Equal Opportunity Employer
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Worksite address
weston, MA, 02193, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.