About this opportunity
United Therapeutics Corporation lists this Senior Scientist, Process Development opportunity in cambridge, Massachusetts. Review the employer’s description below for duties, qualifications and application requirements.
Job description
California, US residents click here. The job details are as follows:
Who We Are
We are the first publicly-traded biotech or pharmaceutical company to take the form of a public benefit corporation. Our public benefit purpose is to provide a brighter future for patients through the development of novel pharmaceutical therapies; and technologies that expand the availability of transplantable organs. United Therapeutics (Nasdaq: UTHR) seeks to travel down the corridors of indifference to develop treatments for rare, deadly diseases. We were founded in 1996 by a family seeking a cure for their daughter’s pulmonary arterial hypertension (PAH). Today, we have six FDA‑approved therapies that treat PAH, pulmonary hypertension associated with interstitial lung disease (PH‑ILD) and neuroblastoma, a rare pediatric cancer. Our near‑term pipeline seeks to develop additional therapies for PAH and pulmonary fibrosis (PF). The cure for end‑stage life‑threatening diseases like PAH, PH‑ILD, PF, and many others is an organ transplant, but only a small percentage of donated organs are available to address the vast need. For this reason, we are working to create manufactured organs to address the shortage of kidneys, hearts, lungs, and livers available for transplant. We believe an unlimited supply of tolerable, transplantable organs will eliminate the transplant waiting list and cure end‑stage organ diseases for which transplant is not currently an option.
Who You Are
At Thymmune, you'll join a team pushing the boundaries of cell therapy and transplant innovation through advanced iPSC‑derived manufacturing technologies. As a Senior Scientist, Process Development, you'll play a pivotal role in designing and optimizing processes that support the development of transformative therapies, helping move breakthrough science from concept to clinic. It's an opportunity to solve tough scientific challenges, collaborate with world‑class colleagues, and contribute to a future where more patients have access to life‑changing treatments.
Design, lead, and optimize iPSC expansion, differentiation, and scale‑up processes to improve process robustness, reproducibility, and product quality
Design and execute development strategies for harvest, downstream processing, formulation, fill‑finish, and fresh/cryopreservation processes to support clinical and commercial manufacturing needs
Lead process characterization studies and author technical documentation to support technology transfer, process validation, and GMP manufacturing readiness
Collaborate cross‑functionally with Analytical Development and other technical teams to define critical process attributes, characterize process performance, and advance process understanding
Design and conduct complex studies to develop and optimize biomaterial‑based cell delivery approaches, formulation strategies, and clinical in‑use hold times
Contribute substantively to FDA and other regulatory submissions by authoring and reviewing technical reports, process development summaries, protocols, risk assessments, and CMC documentation supporting product development and clinical advancement
Analyze, interpret, and communicate experimental results to project teams and leadership, providing scientific recommendations that support program objectives and development decisions
Evaluate emerging scientific literature, technologies, and industry trends to identify opportunities for innovation and continuous improvement within the process development function
Maintain accurate and compliant experimental records and provide scientific guidance, technical expertise, and mentorship to junior scientists and research associates
Perform all other duties as assigned
Minimum Requirements
A Bachelors Degree with 10 years of relevant experience in cell biology, developmental biology, tissue engineering, biomaterials, biomedical engineering or related field
OR a Masters degree with 10 years of relevant experience in in cell biology, developmental biology, tissue engineering, biomaterials, biomedical engineering or related field
OR a PHD with 5 years relevant experience in in cell biology, developmental biology, tissue engineering, biomaterials, biomedical engineering or related field
5+ years of biotech/pharma industry experience
Technical expertise in iPS expansion and differentiation process development
Technical expertise in downstream processing, formulation and stability of cell based products including fresh and cryo formulation development
Experience with laboratory instrumentation and data software; with appropriate word processing, spreadsheet, presentation and related standard software
Experience supporting FDA and/or other regulatory submissions through preparation of technical reports and CMC documentation
Ability to mentor junior scientists and research associates and provide scientific guidance across projects
Ability to design and perform complex and technically challenging experiments
Excellent written, verbal communication and presentation skills
Preferred Qualifications
Doctor of Philosophy (PhD) or a Master’s Degree in biology, cell biology, biomedical engineering, tissue engineering, developmental biology, or related scientific discipline
Experience developing biomaterial‑based cell delivery systems, including hydrogels, injectable matrices, scaffolds, extracellular matrix (ECM)-inspired materials, or other implantable biomaterials
Expertise in automated cell processing equipment such PBS bioreactor, Rotea, Biowelder, Metaflex, NC200, and others
Experience in tech transfer of cell therapy processes to GMP
Salary range
The salary range for this position is $127,500.00 - $170,000.00 and reflects our good‑faith estimate of the compensation for this role at the time of posting. An employee's position within the salary range will be based on factors such as education, qualifications, experience, skills, geographic location, and business needs, as well as other factors permitted by law at the time of posting. This range may be modified in the future based on company and market factors.
Location
This role is based in our Cambridge, MA Thymmune location. At United Therapeutics, our mission and vision are one. We use our enthusiasm, creativity, and persistence to innovate for the unmet medical needs of our patients and to benefit our other stakeholders. We are bold and unconventional. We have fun, we do good.
Benefits
Eligible employees may participate in the Company's comprehensive benefits suite of programs, including medical / dental / vision / prescription coverage, employee wellness resources, savings plans (401k and ESPP), paid time off & paid parental leave benefits, disability benefits, and more. For additional information on Company benefits, please visit
Equal Opportunity Employer
United Therapeutics Corporation is an Equal Opportunity Employer, including veterans and individuals with disabilities. We strive to be an organization that engages the minds, hearts, and most spirited efforts of each of our employees. Our sense of purpose transforms what we do from work into mission, occupation into vocation and achievement into success. We challenge our employees with innovative and revolutionary projects, offer an environment which fosters high‑level job performance and provide a highly competitive total rewards package. This is what makes United Therapeutics a stimulating place to work.
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Worksite address
cambridge, MA, 02140, US
Who can apply
Review the original listing for work authorization, qualifications and employer requirements.